LAMA_000052500

RNA pseudouridylate synthase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_185520 OG7: OG7_0001865 79 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 79 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000637100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000115400 ⚠
Hsp70 protein/Tetratricopeptide repeat, putat
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000524500 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000487100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000812000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000603500 ⚠
FYVE zinc finger/Phosphatidylinositol 3- and
— OG7
LAMA_000590800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000384900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000106900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000600400 ⚠
Flavoprotein, putative
— OG7
LAMA_000636400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000743000 ⚠
EAP30/Vps36 family, putative
— OG7
LAMA_000593700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000616200 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000371900 ⚠
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000421900 ⚠
Acetyltransferase (GNAT) family/Acetyltransfe
— OG7
LAMA_000196400 ⚠
Acetyltransferase (GNAT) family/Acetyltransfe
— OG7
LAMA_000268100 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
LAMA_000291700 ⚠
CrtC N-terminal lipocalin domain/Lipocalin-li
— OG7
LAMA_000273000 ⚠
ZPR1 zinc-finger domain containing protein, p
— OG7
LAMA_000081500 ⚠
Ctf8, putative
— OG7
LAMA_000507100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000486500 ⚠
DNL zinc finger containing protein, putative
— OG7
LAMA_000181300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000271800 ⚠
Methyltransferase domain containing protein,
— OG7
LAMA_000733800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000069200 ⚠
Cyclin, putative
— OG7
LAMA_000473200 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000621600 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000662400 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000703300 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000703100 ⚠
hypothetical protein
— OG7
LAMA_000473100 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000780200 ⚠
TATA box binding protein associated factor (T
— OG7
LAMA_000225400 ⚠
TATA box binding protein associated factor (T
— OG7
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— OG7
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000488800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000064000 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.