LAMA_000271800

Methyltransferase domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_144101 OG7: OG7_0006136 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000264000 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000264200 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000749800 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000107800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— Both
LAMA_000198900 ⚠
hypothetical protein, conserved
— Both
LAMA_000268100
Phosphorylated CTD interacting factor 1 WW do
— Both
LAMA_000031500
Aspartyl protease/gag-polyprotein putative as
— Both
LAMA_000196400 ⚠
Acetyltransferase (GNAT) family/Acetyltransfe
— Both
LAMA_000780200 ⚠
TATA box binding protein associated factor (T
— Both
LAMA_000225400 ⚠
TATA box binding protein associated factor (T
— Both
LAMA_000052500 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAMA_000421900 ⚠
Acetyltransferase (GNAT) family/Acetyltransfe
— OG7
LAMA_000069200 ⚠
Cyclin, putative
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000487100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000621600 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000662400 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000703300 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000703100 ⚠
hypothetical protein
— OG7
LAMA_000147600 ⚠
Acyl CoA binding protein, putative
— Both
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000559100 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000473100 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000334500 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG6
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— Both
LAMA_000636400
hypothetical protein, conserved
— Both
LAMA_000743000
EAP30/Vps36 family, putative
— Both
LAMA_000616200
tRNA (Guanine-1)-methyltransferase, putative
— Both
LAMA_000633600 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000740600
hypothetical protein, conserved
— Both
LAMA_000789300
Helicase conserved C-terminal domain containi
— OG6
LAMA_000605600
Calpain family cysteine protease, putative
— OG6
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000545300
hypothetical protein, conserved
— Both
LAMA_000369100
hypothetical protein, conserved
— Both
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— +1 more Both
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
LAMA_000232500
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.