LAMA_000464300

AKAP7 2'5' RNA ligase-like domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_163296 OG7: OG7_0051916 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000392300 ⚠
Myotubularin-like phosphatase domain containi
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000059100 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000241600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000668200 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000450700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000187400 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LAMA_000711100 ⚠
Glutathione S-transferase, N-terminal domain/
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000138300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— Both
LAMA_000088800
Eukaryotic membrane protein family, putative
— Both
LAMA_000766700
WD domain, G-beta repeat/Coatomer WD associat
— Both
LAMA_000363400
hypothetical protein, conserved
— Both
LAMA_000377800
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000789100
hypothetical protein, conserved
— Both
LAMA_000522900
hypothetical protein, conserved
— Both
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000809900 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— OG7
LAMA_000127800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000456400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000738700 ⚠
Myosin head (motor domain), putative
— Both
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000693600 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000221400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000157700
hypothetical protein, conserved
— Both
LAMA_000440400
hypothetical protein, conserved
— Both
LAMA_000197500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— Both
LAMA_000267800 ⚠
N-terminal helicase PWI domain/DEAD/DEAH box
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.