LAMA_000766700

WD domain, G-beta repeat/Coatomer WD associated region/Coatomer (COPI) alpha subunit C-terminus, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101600 OG7: OG7_0006188 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000581500
Adaptin N terminal region/Coatomer gamma subu
— Both
LAMA_000416900 ⚠
Proteasome subunit A N-terminal signature/Pro
— Both
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000800300
Putative death-receptor fusion protein (DUF24
— Both
LAMA_000541800 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more Both
LAMA_000372600
hypothetical protein, conserved
— Both
LAMA_000688200 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more Both
LAMA_000751700
RNA-binding signal recognition particle 68, p
— Both
LAMA_000408000 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more Both
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000805000 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more Both
LAMA_000377000 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more Both
LAMA_000494200
hypothetical protein, conserved
— Both
LAMA_000525000
Zn-finger in Ran binding protein and others/S
— Both
LAMA_000464300
AKAP7 2'5' RNA ligase-like domain containing
— Both
LAMA_000409400
hypothetical protein, conserved
— Both
LAMA_000757500
hypothetical protein, conserved
— Both
LAMA_000224700
WD domain, G-beta repeat, putative
— Both
LAMA_000814900 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000809900 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— OG7
LAMA_000127800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000456400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000221400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000172800 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000048200
hypothetical protein, conserved
— Both
LAMA_000322400 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000213000 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000416000 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000530500 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000693600 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000187400 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LAMA_000711100 ⚠
Glutathione S-transferase, N-terminal domain/
— OG7
LAMA_000209500 ⚠
TCP-1/cpn60 chaperonin family, putative
— +3 more OG7
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000728400
WD domain, G-beta repeat/Coatomer WD associat
— Both
LAMA_000098000
hypothetical protein, conserved
— Both
LAMA_000391000
Adaptin N terminal region/Coatomer beta C-ter
— Both
LAMA_000355600
WD domain, G-beta repeat, putative
— Both
LAMA_000377600
hypothetical protein, conserved
— Both
LAMA_000377800
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000773400
hypothetical protein, conserved
— Both
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— Both
LAMA_000493800
ER-Golgi trafficking TRAPP I complex 85 kDa s
— Both
LAMA_000737100 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000021900 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000790400
hypothetical protein, conserved
— Both
LAMA_000285600 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.