LAMA_000444200

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147390 OG7: OG7_0043934 14 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 14 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000171400
Seryl-tRNA synthetase N-terminal domain/tRNA
— Both
LAMA_000020000 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— Both
LAMA_000618600
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— Both
LAMA_000574200
X-Pro dipeptidyl-peptidase (S15 family)/Serin
— Both
LAMA_000338600 ⚠
14-3-3 protein, putative
— Both
LAMA_000113600
hypothetical protein, conserved
— Both
LAMA_000173900 ⚠
14-3-3 protein, putative
— Both
LAMA_000389500
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000171900
hypothetical protein, conserved
— Both
LAMA_000194500 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— Both
LAMA_000268100
Phosphorylated CTD interacting factor 1 WW do
— Both
LAMA_000285600 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— Both
LAMA_000067000
ATP synthase alpha/beta family, nucleotide-bi
— Both
LAMA_000809900 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.