LAMA_000171400

Seryl-tRNA synthetase N-terminal domain/tRNA synthetase class II core domain (G, H, P, S and T), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100275 OG7: OG7_0002999 26 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 26 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000574200
X-Pro dipeptidyl-peptidase (S15 family)/Serin
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000444200
hypothetical protein, conserved
— Both
LAMA_000194500 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— Both
LAMA_000389500
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000173900 ⚠
14-3-3 protein, putative
— Both
LAMA_000113600
hypothetical protein, conserved
— Both
LAMA_000338600 ⚠
14-3-3 protein, putative
— Both
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000618600
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— Both
LAMA_000020000 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— Both
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000054500
Lyase/Adenylosuccinate lyase C-terminal, puta
— Both
LAMA_000781200
TGS domain/Threonyl and Alanyl tRNA synthetas
— Both
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— Both
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— Both
LAMA_000119300
Amidohydrolase family, putative
— Both
LAMA_000186300
tRNA synthetases class I (C) catalytic domain
— Both
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.