LAMA_000065900

Tetratricopeptide repeat, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101939 OG7: OG7_0003813 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000053900 ⚠
Anaphase-promoting complex, subunit 10 (APC10
— +2 more Both
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— Both
LAMA_000085800 ⚠
hypothetical protein, conserved
— Both
LAMA_000593000 ⚠
Tetratricopeptide repeat, putative
— +2 more Both
LAMA_000605100 ⚠
hypothetical protein, conserved
— +2 more Both
LAMA_000463100 ⚠
hypothetical protein, conserved
— +2 more Both
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000592700 ⚠
Phosphatidylinositol-specific phospholipase C
— OG7
LAMA_000618200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat/Ank
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000656800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000554300 ⚠
Prp19/Pso4-like/WD domain, G-beta repeat, put
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000433700 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000315800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000390000 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAMA_000055100 ⚠
Ankyrin repeat/DHHC palmitoyltransferase, put
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000766400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000742500 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000415700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000116800 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000247700 ⚠
RING-H2 zinc finger domain/Anaphase-promoting
— OG7
LAMA_000394800 ⚠
Anaphase-promoting complex subunit 11 RING-H2
— OG7
LAMA_000469800 ⚠
Anaphase-promoting complex subunit 11 RING-H2
— OG7
LAMA_000247800 ⚠
Ring finger domain/RING-H2 zinc finger domain
— OG7
LAMA_000409000 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAMA_000686900 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAMA_000057000 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000370200 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAMA_000262000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000116000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000793100 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000696200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.