LAMA_000415700

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_158062 OG7: OG7_0052254 104 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 104 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000065900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000214400 ⚠
Cys/Met metabolism PLP-dependent enzyme, puta
— Both
LAMA_000195600
Lipase (class 3), putative
— Both
LAMA_000055500
Tetratricopeptide repeat, putative
— Both
LAMA_000050100 ⚠
MORN repeat, putative
— Both
LAMA_000063900
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— Both
LAMA_000253200
hypothetical protein, conserved
— Both
LAMA_000261700
Ring finger domain containing protein, putati
— Both
LAMA_000299400
Phe-tRNA synthetase beta subunit B1 domain/B3
— Both
LAMA_000057000
Axonemal dynein light chain, putative
— Both
LAMA_000296300 ⚠
hypothetical protein
— OG6
LAMA_000024000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG6
LAMA_000296100 ⚠
hypothetical protein
— OG6
LAMA_000296400 ⚠
hypothetical protein, conserved
— OG6
LAMA_000097900
Domain of unknown function (DUF3437), putativ
— Both
LAMA_000085800
hypothetical protein, conserved
— Both
LAMA_000283700
Hydantoinase/oxoprolinase N-terminal region/H
— Both
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— Both
LAMA_000153100
ATPase family associated with various cellula
— Both
LAMA_000073300 ⚠
MORN repeat, putative
— OG7
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000207800 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000154000 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000544800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000799000 ⚠
Cys/Met metabolism PLP-dependent enzyme/DegT/
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.