LAMA_000390000

Raptor N-terminal CASPase like domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147359 OG7: OG7_0005815 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000657400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000667900 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
LAMA_000586100 ⚠
MATH domain containing protein, putative
— OG7
LAMA_000653500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000591000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000105900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000605100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000607500 ⚠
GYF domain 2/DnaJ domain containing protein,
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000184900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000031300 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000031200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000055500 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000380900 ⚠
AAA domain (dynein-related subfamily)/Midasin
— OG7
LAMA_000463100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000474100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000474000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000236800 ⚠
Cyclic nucleotide-binding domain/PAS fold/Pro
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000031400 ⚠
hypothetical protein
— OG7
LAMA_000332300 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000257100 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000572300 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000694100 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000079400 ⚠
hypothetical protein, conserved
— Both
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000063900 ⚠
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— OG7
LAMA_000153100 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000132800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000065900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000249400 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— OG7
LAMA_000742500 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000197300 ⚠
hypothetical protein, conserved
— Both
LAMA_000679800 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.