LAMA_000462900

MCM N-terminal domain/MCM OB domain/MCM P-loop domain/Magnesium chelatase, subunit ChlI/MCM AAA-lid domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102165 OG7: OG7_0001163 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000578900 ⚠
MCM OB domain/MCM P-loop domain/Magnesium che
— +18 more Both
LAMA_000142100 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— +18 more Both
LAMA_000684700 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— +18 more Both
LAMA_000065200 ⚠
MCM OB domain/MCM P-loop domain/AAA domain (d
— +18 more Both
LAMA_000563800 ⚠
Mini-chromosome maintenance protein 2/MCM N-t
— +18 more Both
LAMA_000723300 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— +18 more Both
LAMA_000815500 ⚠
MCM OB domain/MCM P-loop domain/MCM AAA-lid d
— +17 more OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000093300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000109600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000356900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000681500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000079700 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000173000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000245300 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000126100 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000684500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276600 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000174400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000487900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000433700 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000019300 ⚠
Cullin family, putative
— OG7
LAMA_000253800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000349100 ⚠
GINS complex protein, putative
— Both
LAMA_000175100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000055500 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000493000 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LAMA_000051500 ⚠
KH domain containing protein, putative
— OG7
LAMA_000508100 ⚠
Myosin-like coiled-coil protein, putative
— OG7
LAMA_000215700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000149500 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
LAMA_000278600 ⚠
Flagellar-associated PapD-like, putative
— OG7
LAMA_000174100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000247900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000281500 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
LAMA_000019100 ⚠
PRP38 family, putative
— OG7
LAMA_000475500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000182700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000477400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000576100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.