LAMA_000343500

NUDIX domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101523 OG7: OG7_0006514 88 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 88 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000543600 ⚠
Phosphotransferase enzyme family/Choline/etha
— OG7
LAMA_000304300 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000126200 ⚠
non-haem dioxygenase in morphine synthesis N-
— OG7
LAMA_000543800 ⚠
Snf7, putative
— OG7
LAMA_000157600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000199500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000669600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000116600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000429600 ⚠
ChaC-like protein, putative
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000691700
Enoyl-CoA hydratase/isomerase, putative
— OG7
LAMA_000159700
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000283100
UTP--glucose-1-phosphate uridylyltransferase,
— Both
LAMA_000519400
hypothetical protein, conserved
— Both
LAMA_000458500
hypothetical protein, conserved
— Both
LAMA_000495100
hypothetical protein, conserved
— Both
LAMA_000447100
HIT domain containing protein, putative
— Both
LAMA_000777400 ⚠
hypothetical protein, conserved
— Both
LAMA_000606300
Iron-containing alcohol dehydrogenase, putati
— Both
LAMA_000636500
hypothetical protein, conserved
— Both
LAMA_000621200 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000753600 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000620400 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000061800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000546300 ⚠
Protein tyrosine kinase/Fungal protein kinase
— OG7
LAMA_000493900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000777200 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000141900
AAA domain (dynein-related subfamily)/AAA dom
— OG7
LAMA_000226700 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000378300 ⚠
PSP1 C-terminal conserved region containing p
— Both
LAMA_000227000 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000529900 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LAMA_000226900 ⚠
hypothetical protein
— OG7
LAMA_000777600 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000759400 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAMA_000517300 ⚠
Peptidase family M3, putative
— OG7
LAMA_000595100 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAMA_000040500 ⚠
Peptidase family M3, putative
— OG7
LAMA_000574300 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000371900
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000174300
hypothetical protein, conserved
— Both
LAMA_000702600
WD domain, G-beta repeat, putative
— Both
LAMA_000387000 ⚠
ARD/ARD' family/AraC-like ligand binding doma
— Both
LAMA_000030100
Isochorismatase family, putative
— Both
LAMA_000767800 ⚠
ARD/ARD' family, putative
— Both
LAMA_000429500 ⚠
ChaC-like protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.