LAMA_000227100

Protein phosphatase 2C, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_136388 OG7: OG7_0000783 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000319800
Cell division protein 48 (CDC48), N-terminal
— OG6
LAMA_000042000
ABC transporter, putative
— OG6
LAMA_000377600
hypothetical protein, conserved
— OG6
LAMA_000281400
hypothetical protein, conserved
— OG6
LAMA_000685500
Leucine-rich repeat/Leucine Rich repeats (2 c
— OG6
LAMA_000803800
hypothetical protein, conserved
— OG6
LAMA_000562000
SNARE associated Golgi protein, putative
— OG6
LAMA_000435100
hypothetical protein, conserved
— OG6
LAMA_000634500
Protein of unknown function (DUF3638)/Protein
— OG6
LAMA_000154200
Paraflagellar rod protein, putative
— OG6
LAMA_000777300
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000693600
Myosin head (motor domain), putative
— OG6
LAMA_000746000
Glycosyl hydrolase family 65 central catalyti
— OG6
LAMA_000358700
Glycosyl hydrolase family 65, N-terminal doma
— OG6
LAMA_000452400
hypothetical protein, conserved
— OG6
LAMA_000464700 ⚠
Helicase conserved C-terminal domain/Helicase
— OG6
LAMA_000779000 ⚠
DEAD/DEAH box helicase/AAA domain/Helicase co
— OG6
LAMA_000334500 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG6
LAMA_000461200
HAD domain in Swiss Army Knife RNA repair pro
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.