LAMA_000677300

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_124605 OG7: OG7_0042999 15 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 15 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000256500
hypothetical protein, conserved
— Both
LAMA_000705000
Nicotinate phosphoribosyltransferase (NAPRTas
— Both
LAMA_000435000
Arginase family, putative
— OG6
LAMA_000703600 ⚠
NADH:flavin oxidoreductase / NADH oxidase fam
— OG6
LAMA_000814100
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000655000
Myristoyl-CoA:protein N-myristoyltransferase,
— Both
LAMA_000191500 ⚠
NADH:flavin oxidoreductase / NADH oxidase fam
— Both
LAMA_000191600 ⚠
NADH:flavin oxidoreductase / NADH oxidase fam
— Both
LAMA_000317200
3-hydroxyacyl-CoA dehydrogenase, NAD binding
— Both
LAMA_000678800
hypothetical protein, conserved
— Both
LAMA_000438300
Alcohol dehydrogenase GroES-like domain/D-iso
— Both
LAMA_000450900
Ran-interacting Mog1 protein, putative
— Both
LAMA_000767800 ⚠
ARD/ARD' family, putative
— OG7
LAMA_000387000 ⚠
ARD/ARD' family/AraC-like ligand binding doma
— OG7
LAMA_000781700
Arginase family, putative
— OG7
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.