LAMA_000395100

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_157104 OG7: OG7_0033971 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000108200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000273700 ⚠
PPR repeat/Pentatricopeptide repeat domain/PP
— OG7
LAMA_000418900 ⚠
BAG domain containing protein, putative
— OG7
LAMA_000796100 ⚠
PPR repeat, putative
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000590600 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000580200 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000083600 ⚠
SIS domain containing protein, putative
— OG7
LAMA_000070300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000771500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000107300 ⚠
Thioredoxin-like domain/UDP-glucose:Glycoprot
— OG7
LAMA_000812000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000465900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000348100 ⚠
Glycosyl hydrolases family 31, putative
— OG7
LAMA_000652100 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000420500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000592400 ⚠
Histidyl-tRNA synthetase/Anticodon binding do
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000620000 ⚠
DNA ligase N terminus/ATP dependent DNA ligas
— OG7
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— OG7
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000763300 ⚠
Adaptin N terminal region/Adaptin C-terminal
— OG7
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— OG7
LAMA_000511500 ⚠
Glucosidase II beta subunit-like protein, put
— OG7
LAMA_000016600 ⚠
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— OG7
LAMA_000499400 ⚠
Translation initiation factor eIF3 subunit, p
— OG7
LAMA_000793800 ⚠
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— OG7
LAMA_000136400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000175800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000553600 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000651000 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000304300 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000597400 ⚠
Armadillo/beta-catenin-like repeat/Atypical A
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000087800 ⚠
Adaptin N terminal region containing protein,
— OG7
LAMA_000647700 ⚠
Calreticulin family, putative
— OG7
LAMA_000574300 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.