LAMA_000620000

DNA ligase N terminus/ATP dependent DNA ligase domain/ATP dependent DNA ligase C terminal region containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100906 OG7: OG7_0002598 154 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 154 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000641300 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000048000 ⚠
Ubiquitin-like domain containing protein, put
— Both
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— Both
LAMA_000112500 ⚠
XPC-binding domain/UBA/TS-N domain containing
— Both
LAMA_000532300 ⚠
hypothetical protein
— Both
LAMA_000018800 ⚠
PCRF domain/RF-1 domain containing protein, p
— Both
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000416500 ⚠
hypothetical protein, conserved
— Both
LAMA_000618600 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— Both
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— Both
LAMA_000273700 ⚠
PPR repeat/Pentatricopeptide repeat domain/PP
— Both
LAMA_000430000 ⚠
Elongation factor Tu GTP binding domain/50S r
— Both
LAMA_000537300 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000616600 ⚠
Adenosylmethionine decarboxylase, putative
— Both
LAMA_000571100 ⚠
Thiamine pyrophosphate enzyme, N-terminal TPP
— Both
LAMA_000012300
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000432800 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— Both
LAMA_000559100 ⚠
RNB domain containing protein, putative
— Both
LAMA_000399500 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LAMA_000572900 ⚠
OB-fold nucleic acid binding domain/Replicati
— Both
LAMA_000428900 ⚠
Beta-lactamase superfamily domain containing
— Both
LAMA_000428800 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LAMA_000694600 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LAMA_000070300 ⚠
hypothetical protein, conserved
— Both
LAMA_000452900 ⚠
hypothetical protein, conserved
— Both
LAMA_000047800 ⚠
TatD related DNase, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000162100 ⚠
Alcohol dehydrogenase GroES-like domain/Zinc-
— OG7
LAMA_000522100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000131800 ⚠
Isochorismatase family, putative
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000792600 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000801900 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000655200 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.