LAMA_000012300

Protein kinase domain/Protein tyrosine kinase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_128066 OG7: OG7_0000396 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000595900
Mitochondrial glycoprotein, putative
— OG6
LAMA_000744000
Regulator of chromosome condensation (RCC1) r
— OG6
LAMA_000604900
C2H2 type zinc-finger (2 copies), putative
— OG6
LAMA_000508300
hypothetical protein, conserved
— OG6
LAMA_000620000
DNA ligase N terminus/ATP dependent DNA ligas
— OG6
LAMA_000538300
XRN 5'-3' exonuclease N-terminus, putative
— OG6
LAMA_000246900
Aspartate/ornithine carbamoyltransferase, car
— OG6
LAMA_000791100
HECT-domain (ubiquitin-transferase), putative
— OG6
LAMA_000746200
AAA domain/DEAD/DEAH box helicase/Helicase co
— OG6
LAMA_000705800
Protein prenyltransferase alpha subunit repea
— OG6
LAMA_000428900 ⚠
Beta-lactamase superfamily domain containing
— OG6
LAMA_000064000
Ferrous iron transport protein B/50S ribosome
— OG6
LAMA_000498900
Elongation factor Tu GTP binding domain/Elong
— OG6
LAMA_000204800
Thiamin pyrophosphokinase, vitamin B1 binding
— OG6
LAMA_000764200
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000641300
Dihydrouridine synthase (Dus), putative
— OG6
LAMA_000711900 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG6
LAMA_000642000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG6
LAMA_000616300
GHMP kinases N terminal domain/GHMP kinases C
— OG6
LAMA_000537300
WD domain, G-beta repeat, putative
— OG6
LAMA_000132000
Isochorismatase family, putative
— OG6
LAMA_000088300
Insulinase (Peptidase family M16)/Peptidase M
— OG6
LAMA_000171100
hypothetical protein, conserved
— OG6
LAMA_000236500
Transcription factor IIB C-terminal module 1,
— OG6
LAMA_000047800
TatD related DNase, putative
— OG6
LAMA_000046300
Methylmalonyl Co-A mutase-associated GTPase M
— OG6
LAMA_000428800 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— OG6
LAMA_000162000
Alcohol dehydrogenase GroES-like domain/Zinc-
— OG6
LAMA_000069500
Vta1 like/Vta1 C-terminal domain containing p
— OG6
LAMA_000018100
Casein kinase II regulatory subunit, putative
— OG6
LAMA_000442100
Galactose oxidase, central domain containing
— OG6
LAMA_000591400
N-acetyltransferase B complex (NatB) non cata
— OG6
LAMA_000572900
OB-fold nucleic acid binding domain/Replicati
— OG6
LAMA_000767200
hypothetical protein, conserved
— OG6
LAMA_000751900
Cytosolic carboxypeptidase N-terminal domain/
— OG6
LAMA_000727000
Tyrosyl-DNA phosphodiesterase, putative
— OG6
LAMA_000072200
Rhodanese-like domain/Domain of unknown funct
— OG6
LAMA_000506700 ⚠
NUBPL iron-transfer P-loop NTPase/Anion-trans
— OG6
LAMA_000385100
hypothetical protein, conserved
— OG6
LAMA_000064300
Iron only hydrogenase large subunit, C-termin
— OG6
LAMA_000751300
Methyltransferase involved in Williams-Beuren
— OG6
LAMA_000567800
hypothetical protein, conserved
— OG6
LAMA_000442500 ⚠
ThiF family/Ubiquitin-activating enzyme activ
— OG6
LAMA_000575000
hypothetical protein, conserved
— OG6
LAMA_000579900 ⚠
NUBPL iron-transfer P-loop NTPase/VirC1 prote
— OG6
LAMA_000784000
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000399500
Programmed cell death protein 2, C-terminal p
— OG6
LAMA_000385200
Tubulin-tyrosine ligase family, putative
— OG6
LAMA_000040200 ⚠
ATPase family associated with various cellula
— OG6
LAMA_000115700
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.