LAMA_000777700

Protein tyrosine kinase/Protein kinase domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_139053 OG7: OG7_0000003 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000771500
hypothetical protein, conserved
— OG6
LAMA_000620000
DNA ligase N terminus/ATP dependent DNA ligas
— OG6
LAMA_000083600
SIS domain containing protein, putative
— OG6
LAMA_000420500
hypothetical protein, conserved
— OG6
LAMA_000647700
Calreticulin family, putative
— OG6
LAMA_000760900
hypothetical protein, conserved
— OG6
LAMA_000112500
XPC-binding domain/UBA/TS-N domain containing
— OG6
LAMA_000175800
hypothetical protein, conserved
— OG6
LAMA_000747000
Glutaminyl-tRNA synthetase, non-specific RNA
— OG6
LAMA_000618600
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG6
LAMA_000511500
Glucosidase II beta subunit-like protein, put
— OG6
LAMA_000203600
tRNA synthetases class I (I, L, M and V)/tRNA
— OG6
LAMA_000608600
SET domain containing protein, putative
— OG6
LAMA_000616800
tRNA synthetases class I (I, L, M and V)/tRNA
— OG6
LAMA_000597400
Armadillo/beta-catenin-like repeat/Atypical A
— OG6
LAMA_000611000 ⚠
Formate--tetrahydrofolate ligase, putative
— OG6
LAMA_000505600 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG6
LAMA_000107300
Thioredoxin-like domain/UDP-glucose:Glycoprot
— OG6
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— OG6
LAMA_000070300
hypothetical protein, conserved
— OG6
LAMA_000694600
Gar1/Naf1 RNA binding region containing prote
— OG6
LAMA_000559100
RNB domain containing protein, putative
— OG6
LAMA_000432800
tRNA synthetases class II (A)/Threonyl and Al
— OG6
LAMA_000473300
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG6
LAMA_000418900
BAG domain containing protein, putative
— OG6
LAMA_000553400 ⚠
Tetratricopeptide repeat/Potential Monad-bind
— OG6
LAMA_000306300 ⚠
Tetratricopeptide repeat, putative
— OG6
LAMA_000771900
hypothetical protein, conserved
— OG6
LAMA_000103100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG6
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG6
LAMA_000430000
Elongation factor Tu GTP binding domain/50S r
— OG6
LAMA_000273700
PPR repeat/Pentatricopeptide repeat domain/PP
— OG6
LAMA_000380800 ⚠
Deoxyhypusine synthase, putative
— OG6
LAMA_000657900
hypothetical protein, conserved
— OG6
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— OG6
LAMA_000499400
Translation initiation factor eIF3 subunit, p
— OG6
LAMA_000282000
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000393700
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— OG6
LAMA_000297600
ABC transporter, putative
— OG6
LAMA_000404000
tRNA synthetases class I (I, L, M and V)/tRNA
— OG6
LAMA_000306900
PUB domain containing protein, putative
— OG6
LAMA_000812000
SET domain containing protein, putative
— OG6
LAMA_000793800
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— OG6
LAMA_000732600 ⚠
Deoxyhypusine synthase, putative
— OG6
LAMA_000128200
tRNA synthetases class I (W and Y), putative
— OG6
LAMA_000016600
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— OG6
LAMA_000592200
Cytochrome b5-like Heme/Steroid binding domai
— OG6
LAMA_000225700
SLOG cluster4 family/Possible lysine decarbox
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.