LAMA_000357700

VHS domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_143933 OG7: OG7_0001949 41 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 41 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000103100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000559100 ⚠
RNB domain containing protein, putative
— Both
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000347500
hypothetical protein, conserved
— Both
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000593200 ⚠
GrpE, putative
— Both
LAMA_000591800
hypothetical protein, conserved
— Both
LAMA_000706800
hypothetical protein, conserved
— Both
LAMA_000499400
Translation initiation factor eIF3 subunit, p
— Both
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000592800 ⚠
CS domain containing protein, putative
— OG7
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000593300 ⚠
GrpE, putative
— OG7
LAMA_000647700
Calreticulin family, putative
— Both
LAMA_000225700
SLOG cluster4 family/Possible lysine decarbox
— Both
LAMA_000418900
BAG domain containing protein, putative
— Both
LAMA_000564200
ATP cone domain/Ribonucleotide reductase, all
— Both
LAMA_000776200
hypothetical protein, conserved
— Both
LAMA_000542600
Arginyl tRNA synthetase N terminal domain/tRN
— Both
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000401100
La domain containing protein, putative
— Both
LAMA_000781300
Tetratricopeptide repeat, putative
— Both
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— Both
LAMA_000404000
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000771800
hypothetical protein, conserved
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— Both
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000633600 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000268400
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.