LAMA_000726400

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_200078 OG7: OG7_0084089 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000328100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000026100 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000187600 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000075500 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000415800 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000306000 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000411000 ⚠
Ring finger domain/RING-H2 zinc finger domain
— OG7
LAMA_000143200 ⚠
Ring finger domain/RING-H2 zinc finger domain
— OG7
LAMA_000541100 ⚠
RING-H2 zinc finger domain/Ring finger domain
— OG7
LAMA_000481600 ⚠
Ring finger domain containing protein, putati
— OG7
LAMA_000335500 ⚠
Ring finger domain/RING-like zinc finger/RING
— OG7
LAMA_000258900 ⚠
Anaphase-promoting complex subunit 11 RING-H2
— OG7
LAMA_000181600 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000129500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000797600 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000091100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000157800 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000351000 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000763200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000791100 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000371900
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000661500 ⚠
Leucine rich repeat, putative
— OG7
LAMA_000356200 ⚠
Leucine rich repeat/Leucine-rich repeat, puta
— OG7
LAMA_000619200
EF hand/EF-hand domain pair, putative
— Both
LAMA_000786300 ⚠
U3 small nucleolar RNA-associated protein 6,
— Both
LAMA_000786400 ⚠
hypothetical protein, conserved
— Both
LAMA_000665200 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LAMA_000812000
SET domain containing protein, putative
— Both
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— Both
LAMA_000575700 ⚠
DEAD/DEAH box helicase/Type III restriction e
— Both
LAMA_000513800 ⚠
Leucine Rich repeat, putative
— Both
LAMA_000149400
Fibronectin-binding protein A N-terminus (Fbp
— Both
LAMA_000422500
Rab-GTPase-TBC domain containing protein, put
— Both
LAMA_000600500 ⚠
tRNA pseudouridine synthase, putative
— Both
LAMA_000514500
Cupin-like domain containing protein, putativ
— Both
LAMA_000439600
Glycogen recognition site of AMP-activated pr
— Both
LAMA_000514400
hypothetical protein, conserved
— Both
LAMA_000452000 ⚠
RING-H2 zinc finger domain/Zinc finger, C3HC4
— Both
LAMA_000678700
hypothetical protein, conserved
— Both
LAMA_000707100 ⚠
Pumilio-family RNA binding repeat, putative
— Both
LAMA_000287000 ⚠
Pumilio-family RNA binding repeat, putative
— Both
LAMA_000386700
hypothetical protein, conserved
— Both
LAMA_000068300
Surp module, putative
— Both
LAMA_000719300
PPPDE putative peptidase domain/PUB domain/Gl
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.