LAMA_000411000

Ring finger domain/RING-H2 zinc finger domain/Zinc finger, C3HC4 type (RING finger)/Anaphase-promoting complex subunit 11 RING-H2 finger containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_199865 OG7: OG7_0000431 37 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 37 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000460000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000026100 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000558200 ⚠
ThiF family, putative
— OG7
LAMA_000604900 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LAMA_000722800 ⚠
ThiF family, putative
— OG7
LAMA_000740200 ⚠
Shwachman-Bodian-Diamond syndrome (SBDS) prot
— OG7
LAMA_000791100 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000085500 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000109100 ⚠
Protein prenyltransferase alpha subunit repea
— OG7
LAMA_000279700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000068300 ⚠
Surp module, putative
— OG7
LAMA_000439600 ⚠
Glycogen recognition site of AMP-activated pr
— OG7
LAMA_000694600 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG7
LAMA_000678700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— OG7
LAMA_000386700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000619200 ⚠
EF hand/EF-hand domain pair, putative
— OG7
LAMA_000075500 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000415800 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000707100 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000306000 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000287000 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000665200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000600500 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000514400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000351000 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000726400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000763200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000715300 ⚠
Histone-binding protein RBBP4 or subunit C of
— OG7
LAMA_000187600 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.