LINF_130014300

N(2) - N(2)-dimethylguanosine tRNA methyltransferase - putative
Leishmania infantum JPCM5 OG6: OG6_101071 OG7: OG7_0004550 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_260008100 ⚠
6-phosphofructo-2-kinase/fructose-2 -6-biphos
— OG7
LINF_300037800
hypothetical protein - conserved
— Both
LINF_330027700
ribosome assembly protein RRB1 - putative
— Both
LINF_340044200
vacuolar ATP synthase catalytic subunit A - p
— Both
LINF_180010500
hypothetical protein - conserved
— Both
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— Both
LINF_360039100
ATP synthase - putative
— Both
LINF_300017900
Zinc finger - C3HC4 type (RING finger) contai
— Both
LINF_180017600 ⚠
prolyl-tRNA synthetase - putative
— Both
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— Both
LINF_240026400
tubulin folding cofactor D - putative
— Both
LINF_150006700 ⚠
serine/threonine-protein kinase - putative
— OG7
LINF_330026700 ⚠
dual-specificity protein kinase - putative
— OG7
LINF_290007900 ⚠
zinc-finger of a C2HC-type - putative
— OG7
LINF_190015500 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LINF_180017700 ⚠
prolyl-tRNA synthetase - putative
— Both
LINF_140016900 ⚠
protein kinase - putative
— OG7
LINF_360051800 ⚠
serine/threonine kinase - putative
— OG7
LINF_360010200 ⚠
zinc-finger of a C2HC-type - putative
— OG7
LINF_260009200 ⚠
pseudouridylate synthase-like protein
— OG7
LINF_350023500 ⚠
protein kinase-like protein
— OG7
LINF_050013700 ⚠
zinc-finger of a C2HC-type - putative
— OG7
LINF_360005800 ⚠
leucine carboxyl methyltransferase - putative
— OG7
LINF_360006500 ⚠
6-phosphofructo-2-kinase/fructose-2 -6-bispho
— OG7
LINF_310020400
hypothetical protein - conserved
— OG7
LINF_100006500
hypothetical protein - conserved
— OG7
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— OG7
LINF_140014100 ⚠
protein kinase - putative
— OG7
LINF_300020600 ⚠
pseudouridine synthase A-like protein - putat
— OG7
LINF_280036400
heat shock protein 70 - putative
— OG7
LINF_360051600
paraflagellar rod component - putative
— OG6
LINF_280011900 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG6
LINF_280031400
Vacuolar proton pump subunit B - putative
— Both
LINF_220011300
Uncharacterised protein family UPF0066 - puta
— Both
LINF_220011900
guide RNA associated protein - GAP2 - putativ
— Both
LINF_350013000 ⚠
NADH-dependent fumarate reductase - putative
— Both
LINF_070013500 ⚠
6-phosphofructo-2-kinase/fructose-2 -6-biphos
— Both
LINF_210022900
2-oxoisovalerate dehydrogenase alpha subunit
— Both
LINF_350034700 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LINF_010011200
DNA-damage inducible protein DDI1-like protei
— Both
LINF_210026200 ⚠
protein kinase - putative
— Both
LINF_030013000 ⚠
6-phosphofructo-2-kinase/fructose-2 -6-biphos
— Both
LINF_180018500
hypothetical protein - conserved
— Both
LINF_360063900
branch point binding protein - putative
— Both
LINF_070013900 ⚠
flavoprotein subunit-like protein
— Both
LINF_300038300 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG6
LINF_290008200
TPR repeat/Tetratricopeptide repeat - putativ
— Both
LINF_300008500
kinesin - putative
— OG6
LINF_290005100
transcription factor-like protein
— Both
LINF_350013700
hypothetical protein - conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.