LINF_360006500

6-phosphofructo-2-kinase/fructose-2 -6-bisphosphatas - putative
Leishmania infantum JPCM5 OG6: OG6_129420 OG7: OG7_0002306 142 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 142 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_330012100 ⚠
hypothetical protein - conserved
— OG7
LINF_350034700 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LINF_360005800 ⚠
leucine carboxyl methyltransferase - putative
— OG7
LINF_360074400 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_090013600 ⚠
ubiquitin ligase - putative
— OG7
LINF_200007900 ⚠
developmentally regulated phosphoprotein-like
— OG7
LINF_280032200 ⚠
eukaryotic translation initiation factor 4E -
— OG7
LINF_250030200 ⚠
Leucine rich repeat/Leucine Rich repeats (2 c
— OG7
LINF_300013000 ⚠
hypothetical protein - conserved
— OG7
LINF_150008200 ⚠
ribonucleoprotein p18 - mitochondrial precurs
— OG7
LINF_290008200 ⚠
TPR repeat/Tetratricopeptide repeat - putativ
— OG7
LINF_190021300 ⚠
eukaryotic translation initiation factor-like
— OG7
LINF_180017700 ⚠
prolyl-tRNA synthetase - putative
— OG7
LINF_360017300 ⚠
endonuclease/exonuclease/phosphatase - putati
— OG7
LINF_150019700 ⚠
inositol/phosphatidylinositol phosphatase - p
— OG7
LINF_320007200 ⚠
Histone chaperone Rttp106-like - putative
— OG7
LINF_350029400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_340048700 ⚠
GRIP domain containing protein - putative
— OG7
LINF_350058900 ⚠
isopentenyl-diphosphate delta-isomerase (type
— OG7
LINF_360061200 ⚠
vacuolar protein sorting-associated protein-l
— OG7
LINF_250005000 ⚠
beta galactofuranosyl transferase
— OG7
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— OG7
LINF_350048100 ⚠
synaptojanin (N-terminal domain) - putative
— OG7
LINF_350019000 ⚠
threonyl-tRNA synthetase - putative
— OG7
LINF_330027700 ⚠
ribosome assembly protein RRB1 - putative
— OG7
LINF_350011600 ⚠
vacuolar ATP synthase subunit d - putative
— OG7
LINF_270019200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_180010500 ⚠
hypothetical protein - conserved
— OG7
LINF_140014100 ⚠
protein kinase - putative
— OG7
LINF_260010500 ⚠
galactofuranosyltransferase lpg1-like protein
— OG7
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— OG7
LINF_360039100 ⚠
ATP synthase - putative
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_180017600 ⚠
prolyl-tRNA synthetase - putative
— OG7
LINF_040009600 ⚠
adenylosuccinate lyase - putative
— OG7
LINF_230011500 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_130019800 ⚠
hypothetical protein - conserved
— OG7
LINF_300030700 ⚠
hypothetical protein - conserved
— OG7
LINF_330039400 ⚠
hypothetical protein - conserved
— OG7
LINF_360006300 ⚠
PUB domain containing protein - putative
— OG7
LINF_130007000 ⚠
Triglyceride lipase - putative
— OG7
LINF_360051600 ⚠
paraflagellar rod component - putative
— OG7
LINF_320007000 ⚠
hypothetical protein - conserved
— OG7
LINF_040008600 ⚠
hypothetical protein - conserved
— OG7
LINF_320034300 ⚠
hypothetical protein - conserved
— OG7
LINF_300037800 ⚠
hypothetical protein - conserved
— OG7
LINF_310020400 ⚠
hypothetical protein - conserved
— OG7
LINF_340033600 ⚠
hypothetical protein - conserved
— OG7
LINF_240026400 ⚠
tubulin folding cofactor D - putative
— OG7
LINF_340044200 ⚠
vacuolar ATP synthase catalytic subunit A - p
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.