LINF_230011500

poly(A)-specific ribonuclease PARN - putative
Leishmania infantum JPCM5 OG6: OG6_102215 OG7: OG7_0005534 205 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 205 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_200007900 ⚠
developmentally regulated phosphoprotein-like
— Both
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_340046700 ⚠
Histidine kinase- - DNA gyrase B- - and HSP90
— OG7
LINF_180015800 ⚠
5-oxoprolinase - putative
— Both
LINF_190015700 ⚠
phenylalanyl-tRNA synthetase - putative
— Both
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_120007600 ⚠
cysteinyl-tRNA synthetase - putative
— Both
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— Both
LINF_240026400 ⚠
tubulin folding cofactor D - putative
— Both
LINF_240004000 ⚠
pyruvate dehydrogenase (lipoamide) kinase - p
— +1 more Both
LINF_110008900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LINF_200016900 ⚠
cysteine peptidase - Clan CA - family C2 - pu
— OG6
LINF_110012000 ⚠
aminopeptidase - putative
— Both
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
LINF_130013600 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LINF_210008800 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_110008700 ⚠
Domain of unknown function(DUF2779) - putativ
— OG7
LINF_200012800 ⚠
tubulin-tyrosine ligase - putative
— OG7
LINF_280006500 ⚠
RNA binding protein - putative
— OG7
LINF_350054800 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_360020200 ⚠
The ARF-like 2 binding protein BART - putativ
— Both
LINF_260024300 ⚠
hypothetical protein - conserved
— Both
LINF_360018400 ⚠
fructose-1 -6-bisphosphate aldolase
— OG7
LINF_300028200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_340048100 ⚠
geranylgeranyltransferase - putative
— OG7
LINF_320036500 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_290007600 ⚠
Tubulin-tyrosine ligase family - putative
— OG7
LINF_060009300 ⚠
Fructose-bisphosphate aldolase class-I - puta
— OG7
LINF_240025100 ⚠
WD domain - G-beta repeat/PFU (PLAA family ub
— Both
LINF_160008900 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_280007900 ⚠
DIS3-like exonuclease - putative
— OG7
LINF_050006700 ⚠
dihydrolipoamide branched chain transacylase
— Both
LINF_210027500 ⚠
ATP synthase F1 subunit gamma protein - putat
— Both
LINF_320007200 ⚠
Histone chaperone Rttp106-like - putative
— Both
LINF_340048700 ⚠
GRIP domain containing protein - putative
— Both
LINF_350019000 ⚠
threonyl-tRNA synthetase - putative
— Both
LINF_330027700 ⚠
ribosome assembly protein RRB1 - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_350011600 ⚠
vacuolar ATP synthase subunit d - putative
— Both
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— Both
LINF_180007200 ⚠
RNA-binding protein 29 - putative
— Both
LINF_290016900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— Both
LINF_180018600 ⚠
cholinephosphate cytidylyltransferase A - put
— OG7
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_240013300 ⚠
inositol polyphosphate phosphatase - putative
— OG7
LINF_300017700 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.