LINF_340046700

Histidine kinase- - DNA gyrase B- - and HSP90-like ATPase - putative
Leishmania infantum JPCM5 OG6: OG6_146732 OG7: OG7_0002830 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_190015700 ⚠
phenylalanyl-tRNA synthetase - putative
— OG7
LINF_240026400 ⚠
tubulin folding cofactor D - putative
— OG7
LINF_290031300 ⚠
aspartyl aminopeptidase - putative
— OG7
LINF_230011500 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_360074400 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_350028700 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_120007600 ⚠
cysteinyl-tRNA synthetase - putative
— OG7
LINF_200007900 ⚠
developmentally regulated phosphoprotein-like
— OG7
LINF_240004000 ⚠
pyruvate dehydrogenase (lipoamide) kinase - p
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_050006700 ⚠
dihydrolipoamide branched chain transacylase
— OG7
LINF_090020500 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LINF_090020400 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LINF_210010100 ⚠
vacuolar sorting-associated-like protein
— OG7
LINF_070015700 ⚠
Domain of unknown function (DUF3437) - putati
— OG7
LINF_120008400 ⚠
hypothetical protein - conserved
— OG7
LINF_010011200 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LINF_270020100 ⚠
hypothetical protein - conserved
— OG7
LINF_350013000 ⚠
NADH-dependent fumarate reductase - putative
— OG7
LINF_070013900 ⚠
flavoprotein subunit-like protein
— OG7
LINF_350016700 ⚠
NADH-dependent fumarate reductase - putative
— OG7
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— OG7
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
LINF_060014400 ⚠
arginine N-methyltransferase - type III - put
— OG7
LINF_360007500 ⚠
peptidyl-prolyl cis-trans isomerase - putativ
— OG7
LINF_340016700 ⚠
uracil phosphoribosyltransferase - putative
— OG7
LINF_290018300 ⚠
Hsp70 protein/TPR repeat/Tetratricopeptide re
— OG7
LINF_290005100 ⚠
transcription factor-like protein
— OG7
LINF_230008000 ⚠
pteridine reductase 1
— OG7
LINF_030010800 ⚠
arginine N-methyltransferase - putative
— OG7
LINF_350038500 ⚠
hypothetical protein - conserved
— OG7
LINF_070008200 ⚠
hypothetical protein - conserved
— OG7
LINF_320006800 ⚠
U2 small nuclear ribonucleoprotein 40K - puta
— OG7
LINF_060011000 ⚠
hypothetical protein - conserved
— OG7
LINF_360031600 ⚠
dipeptidyl-peptidase 8-like serine peptidase
— OG7
LINF_310033000 ⚠
uridine kinase-like protein
— OG7
LINF_230006100 ⚠
GDP-mannose pyrophosphorylase
— OG7
LINF_340019200 ⚠
inositol 5-phosphatase-like protein
— OG7
LINF_240013300 ⚠
inositol polyphosphate phosphatase - putative
— OG7
LINF_250023600 ⚠
Leucine-rich repeat/Leucine Rich repeats (2 c
— OG7
LINF_360062100 ⚠
AP-3 complex subunit beta - putative
— OG7
LINF_150008200 ⚠
ribonucleoprotein p18 - mitochondrial precurs
— OG7
LINF_110017600 ⚠
protein transport protein SEC31 - putative
— OG7
LINF_340048700 ⚠
GRIP domain containing protein - putative
— OG7
LINF_150019700 ⚠
inositol/phosphatidylinositol phosphatase - p
— OG7
LINF_360017300 ⚠
endonuclease/exonuclease/phosphatase - putati
— OG7
LINF_280015000 ⚠
oxidoreductase-like protein
— OG7
LINF_220020400 ⚠
fk506-binding protein 1-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.