LINF_230006100

GDP-mannose pyrophosphorylase

Leishmania infantum JPCM5 OG6: OG6_100460 OG7: OG7_0001668 177 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 177 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LINF_060009000 glutamine synthetase - putative	—	OG6 Tb927.7.4970 ↔ Tb927.8.2050 OG6 TCSYLVIO_001811 ↔ TCSYLVIO_007603 OG7 Tb927.7.4970 ↔ Tb927.8.2050 OG7 TCSYLVIO_001811 ↔ TCSYLVIO_007603	Both
LINF_140020000 inositol-3-phosphate synthase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LINF_110007000 ⚠ acidocalcisomal pyrophosphatase	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
LINF_030014200 ⚠ inorganic pyrophosphatase - putative	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
LINF_200007900 ⚠ developmentally regulated phosphoprotein-like	—	OG6 TCSYLVIO_007262 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007603	Both
LINF_210005600 ⚠ BAR domain containing protein - putative	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007603	OG7
LINF_250006800 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007603	Both
LINF_220021600 alanyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007603	Both
LINF_050013400 hypothetical protein - conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007603	Both
LINF_280007900 ⚠ DIS3-like exonuclease - putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	Both
LINF_230011500 ⚠ poly(A)-specific ribonuclease PARN - putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007603	Both
LINF_360074400 ⚠ poly(A)-specific ribonuclease PARN - putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007603	Both
LINF_360066000 isoleucyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007603	Both
LINF_320047000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007603	Both
LINF_100019400 ⚠ hypothetical protein - conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_007603	Both
LINF_260024300 ⚠ hypothetical protein - conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_007603	Both
LINF_250030200 Leucine rich repeat/Leucine Rich repeats (2 c	—	OG6 TCSYLVIO_006421 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006421 ↔ TCSYLVIO_007603	Both
LINF_350011600 vacuolar ATP synthase subunit d - putative	—	OG6 TCSYLVIO_005104 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_007603	Both
LINF_360051600 paraflagellar rod component - putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007603	OG6
LINF_340024900 Zeta toxin - putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010958 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010958	Both
LINF_080009200 WD domain - G-beta repeat - putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010560	Both
LINF_140009900 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010327	Both
LINF_080007200 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010542	Both
LINF_100008100 Exonuclease - putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010944	Both
LINF_080013300 ⚠ mitochondrial DNA polymerase beta	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010588 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010588	Both
LINF_140020100 ⚠ tyrosyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010624	Both
LINF_280030600 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010621	Both
LINF_250031400 hypothetical protein - conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010323	Both
LINF_360006300 PUB domain containing protein - putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009932 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009932	Both
LINF_360039000 hypothetical protein - conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009198	Both
LINF_290005100 transcription factor-like protein	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010728 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010728	Both
LINF_210013900 methionyl-tRNA synthetase	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
LINF_090013600 ubiquitin ligase - putative	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_007603	Both
LINF_230008000 pteridine reductase 1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008848	Both
LINF_290005500 ⚠ tryptophanyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010724	Both
LINF_140019600 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010621	Both
LINF_200021600 tRNA (Uracil-5-)-methyltransferase/Protein-L-	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008409	Both
LINF_050006700 dihydrolipoamide branched chain transacylase	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009880	Both
LINF_210027500 ATP synthase F1 subunit gamma protein - putat	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009375	Both
LINF_170009800 ⚠ Dihydrouridine synthase (Dus) - putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009102	Both
LINF_300010700 hypothetical protein - conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007603	Both
LINF_240026400 tubulin folding cofactor D - putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007603	Both
LINF_310030900 hypothetical protein - conserved	—	OG6 TCSYLVIO_003958 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003958 ↔ TCSYLVIO_007603	Both
LINF_190012900 ⚠ ABC transport system ATP-binding protein - pu	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007603	Both
LINF_280009200 ⚠ rrp44p homologue - putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	OG7
LINF_330034900 ⚠ metallo-peptidase - Clan MF - Family M17	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007603	OG7
LINF_040008400 ⚠ mitochondrial exoribonuclease DSS-1 - putativ	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	OG7
LINF_360010000 ⚠ dihydrouridine synthase domain protein-like p	—	OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009102	OG7
LINF_340046700 ⚠ Histidine kinase- - DNA gyrase B- - and HSP90	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007603	OG7
LINF_010012200 ⚠ ubiquitin activating enzyme - putative	—	OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010542	OG7

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