LINF_230006100

GDP-mannose pyrophosphorylase
Leishmania infantum JPCM5 OG6: OG6_100460 OG7: OG7_0001668 177 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 177 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_060009000
glutamine synthetase - putative
— Both
LINF_140020000
inositol-3-phosphate synthase
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_200007900 ⚠
developmentally regulated phosphoprotein-like
— Both
LINF_210005600 ⚠
BAR domain containing protein - putative
— OG7
LINF_250006800 ⚠
cleavage and polyadenylation specificity fact
— Both
LINF_220021600
alanyl-tRNA synthetase - putative
— Both
LINF_050013400
hypothetical protein - conserved
— Both
LINF_280007900 ⚠
DIS3-like exonuclease - putative
— Both
LINF_230011500 ⚠
poly(A)-specific ribonuclease PARN - putative
— Both
LINF_360074400 ⚠
poly(A)-specific ribonuclease PARN - putative
— Both
LINF_360066000
isoleucyl-tRNA synthetase - putative
— Both
LINF_320047000
Gar1/Naf1 RNA binding region containing prote
— Both
LINF_100019400 ⚠
hypothetical protein - conserved
— Both
LINF_260024300 ⚠
hypothetical protein - conserved
— Both
LINF_250030200
Leucine rich repeat/Leucine Rich repeats (2 c
— Both
LINF_350011600
vacuolar ATP synthase subunit d - putative
— Both
LINF_360051600
paraflagellar rod component - putative
— OG6
LINF_340024900
Zeta toxin - putative
— Both
LINF_080009200
WD domain - G-beta repeat - putative
— Both
LINF_140009900 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LINF_080007200 ⚠
ubiquitin-activating enzyme-like protein
— Both
LINF_100008100
Exonuclease - putative
— Both
LINF_080013300 ⚠
mitochondrial DNA polymerase beta
— Both
LINF_140020100 ⚠
tyrosyl-tRNA synthetase - putative
— Both
LINF_280030600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LINF_250031400
hypothetical protein - conserved
— Both
LINF_360006300
PUB domain containing protein - putative
— Both
LINF_360039000
hypothetical protein - conserved
— Both
LINF_290005100
transcription factor-like protein
— Both
LINF_210013900
methionyl-tRNA synthetase
— Both
LINF_090013600
ubiquitin ligase - putative
— Both
LINF_230008000
pteridine reductase 1
— Both
LINF_290005500 ⚠
tryptophanyl-tRNA synthetase - putative
— Both
LINF_140019600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LINF_200021600
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LINF_050006700
dihydrolipoamide branched chain transacylase
— Both
LINF_210027500
ATP synthase F1 subunit gamma protein - putat
— Both
LINF_170009800 ⚠
Dihydrouridine synthase (Dus) - putative
— Both
LINF_300010700
hypothetical protein - conserved
— Both
LINF_240026400
tubulin folding cofactor D - putative
— Both
LINF_310030900
hypothetical protein - conserved
— Both
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— Both
LINF_280009200 ⚠
rrp44p homologue - putative
— OG7
LINF_330034900 ⚠
metallo-peptidase - Clan MF - Family M17
— OG7
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LINF_340046700 ⚠
Histidine kinase- - DNA gyrase B- - and HSP90
— OG7
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
Page 1 of 4
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.