LINF_330034900

metallo-peptidase - Clan MF - Family M17

Leishmania infantum JPCM5 OG6: OG6_105603 OG7: OG7_0003405 282 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 282 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LINF_200022000 ⚠ amidohydrolase - putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LINF_120015400 ⚠ N-acyl-L-amino acid amidohydrolase	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LINF_200022100 ⚠ amidohydrolase - putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LINF_200022200 ⚠ amidohydrolase - putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LINF_300019400 ⚠ amidohydrolase - putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LINF_310017700 ⚠ amidohydrolase - putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LINF_310017600 ⚠ amidohydrolase - putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG7 LdBPK_110630.1 ↔ LdBPK_201720.1 OG7 LdBPK_110640.1 ↔ LdBPK_201720.1 OG7 LdBPK_110630.1 ↔ LdBPK_201740.1 +4 more	OG7
LINF_080009200 ⚠ WD domain - G-beta repeat - putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	OG7
LINF_300010700 ⚠ hypothetical protein - conserved	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	OG7
LINF_070013900 ⚠ flavoprotein subunit-like protein	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LINF_360049500 ⚠ hypothetical protein - conserved	—	OG6 LdBPK_332700.1 ↔ LdBPK_364240.1 OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008197 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008197 OG7 LdBPK_110630.1 ↔ LdBPK_364240.1 +2 more	Both
LINF_350013000 ⚠ NADH-dependent fumarate reductase - putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LINF_300013000 ⚠ hypothetical protein - conserved	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003145 OG7 LdBPK_110630.1 ↔ LdBPK_300810.1	OG7
LINF_340028800 ⚠ asparaginyl-tRNA synthetase - putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	OG7
LINF_350016700 ⚠ NADH-dependent fumarate reductase - putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LINF_350016600 ⚠ NADH-dependent fumarate reductase - putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LINF_040008400 ⚠ mitochondrial exoribonuclease DSS-1 - putativ	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 OG7 LdBPK_110640.1 ↔ LdBPK_280470.1	OG7
LINF_010011200 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG6 LdBPK_010630.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG7 LdBPK_010630.1 ↔ LdBPK_110630.1 OG7 LdBPK_010630.1 ↔ LdBPK_332700.1 +1 more	Both
LINF_280007900 ⚠ DIS3-like exonuclease - putative	—	OG6 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 +1 more	Both
LINF_280009200 ⚠ rrp44p homologue - putative	—	OG6 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 +1 more	Both
LINF_210016300 ⚠ aspartyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_005560 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	Both
LINF_300009700 ⚠ aspartyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_005560 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	Both
LINF_360066000 ⚠ isoleucyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LINF_310029900 ⚠ ARM-like helical domain-containing protein	—	OG7 LdBPK_110640.1 ↔ LdBPK_312230.1	OG7
LINF_310008400 ⚠ CRAL/TRIO domain containing protein - putativ	—	OG7 LdBPK_110640.1 ↔ LdBPK_310320.1	OG7
LINF_230010200 ⚠ SNF1-related protein kinase regulatory subuni	—	OG7 LdBPK_110640.1 ↔ LdBPK_230530.1	OG7
LINF_220005600 ⚠ transcription factor-like protein	—	OG7 LdBPK_110640.1 ↔ LdBPK_220007.1 OG7 LdBPK_110630.1 ↔ LdBPK_290620.1	OG7
LINF_340025200 ⚠ Regulator of chromosome condensation (RCC1) r	—	OG7 LdBPK_110630.1 ↔ LdBPK_260720.1 OG7 LdBPK_110640.1 ↔ LdBPK_260720.1 OG7 LdBPK_260720.1 ↔ LdBPK_332700.1	OG7
LINF_260030600 ⚠ hypothetical protein	—	OG7 LdBPK_110640.1 ↔ LdBPK_291830.1	OG7
LINF_280025500 ⚠ p21-C-terminal region-binding protein - putat	—	OG7 LdBPK_110640.1 ↔ LdBPK_282030.1	OG7
LINF_330037100 ⚠ Concanavalin A-like lectin/glucanases superfa	—	OG7 LdBPK_110630.1 ↔ LdBPK_332920.1	OG7
LINF_050012300 ⚠ CYC2-like cyclin - putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_241960.1 OG7 LdBPK_110640.1 ↔ LdBPK_241960.1 OG7 LdBPK_241960.1 ↔ LdBPK_332700.1	OG7
LINF_290023700 ⚠ MORN repeat - putative	—	OG7 LdBPK_110640.1 ↔ LdBPK_291830.1	OG7
LINF_350022300 ⚠ ubiquitin hydrolase - putative	—	OG7 LdBPK_332700.1 ↔ LdBPK_343890.1	OG7
LINF_110014600 ⚠ Leucine Rich repeat - putative	—	OG7 LdBPK_110640.1 ↔ LdBPK_110890.1	OG7
LINF_220010000 ⚠ Acetyltransferase (GNAT) family - putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_130260.1 OG7 LdBPK_110640.1 ↔ LdBPK_130260.1 OG7 LdBPK_130260.1 ↔ LdBPK_332700.1	OG7
LINF_030005400 ⚠ Met-10+ like-protein/Methyltransferase small	—	OG7 LdBPK_110630.1 ↔ LdBPK_160320.1 OG7 LdBPK_110640.1 ↔ LdBPK_160320.1 OG7 LdBPK_160320.1 ↔ LdBPK_332700.1	OG7
LINF_140018100 ⚠ ras-like small GTPases - putative	—	OG7 LdBPK_110640.1 ↔ LdBPK_180610.1	OG7
LINF_260029000 ⚠ hypothetical protein - conserved	—	OG7 LdBPK_110630.1 ↔ LdBPK_262370.1	OG7
LINF_260017600 ⚠ hypothetical protein - conserved	—	OG7 LdBPK_110640.1 ↔ LdBPK_180610.1	OG7
LINF_230026400 ⚠ neutral sphingomyelinase activation associate	—	OG7 LdBPK_110630.1 ↔ LdBPK_332920.1	OG7
LINF_250014500 ⚠ protein kinase - putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_331490.1 OG7 LdBPK_110640.1 ↔ LdBPK_331490.1 OG7 LdBPK_331490.1 ↔ LdBPK_332700.1	OG7
LINF_150020800 ⚠ ubiquitin hydrolase - putative	—	OG7 LdBPK_332700.1 ↔ LdBPK_343890.1	OG7
LINF_170017500 ⚠ hypothetical protein - conserved	—	OG7 LdBPK_110630.1 ↔ LdBPK_171130.1	OG7
LINF_180011800 ⚠ PA26 p53-induced protein (sestrin) - putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_180660.1	OG7
LINF_330014700 ⚠ G1 cyclin CycE4 - putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_241960.1 OG7 LdBPK_110640.1 ↔ LdBPK_241960.1 OG7 LdBPK_241960.1 ↔ LdBPK_332700.1	OG7
LINF_190022000 ⚠ inosine-5'-monophosphate dehydrogenase	—	OG7 LdBPK_110640.1 ↔ LdBPK_191590.1	OG7
LINF_250030200 ⚠ Leucine rich repeat/Leucine Rich repeats (2 c	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_006421	OG7
LINF_150008200 ⚠ ribonucleoprotein p18 - mitochondrial precurs	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_002426	OG7
LINF_360017300 ⚠ endonuclease/exonuclease/phosphatase - putati	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007569	OG7

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