LINF_360066000

isoleucyl-tRNA synthetase - putative

Leishmania infantum JPCM5 OG6: OG6_100811 OG7: OG7_0003029 197 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 197 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LINF_330034900 ⚠ metallo-peptidase - Clan MF - Family M17	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LINF_110011900 ⚠ aminopeptidase - putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LINF_110012000 ⚠ aminopeptidase - putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LINF_140020100 ⚠ tyrosyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 Tb927.10.9190 ↔ Tb927.8.5330	Both
LINF_130016000 leucyl-tRNA synthetase - putative	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
LINF_220010200 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LINF_160016900 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LINF_340028800 ⚠ asparaginyl-tRNA synthetase - putative	—	OG6 Tb927.10.9190 ↔ Tb927.4.2310 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 +1 more	Both
LINF_200022000 ⚠ amidohydrolase - putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LINF_120015400 ⚠ N-acyl-L-amino acid amidohydrolase	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LINF_200022100 ⚠ amidohydrolase - putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LINF_200022200 ⚠ amidohydrolase - putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LINF_300019400 ⚠ amidohydrolase - putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LINF_310017700 ⚠ amidohydrolase - putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LINF_210016300 ⚠ aspartyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LINF_300009700 ⚠ aspartyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LINF_310017600 ⚠ amidohydrolase - putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	OG7
LINF_230006100 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007603	Both
LINF_120017200 ⚠ MYND finger/SET domain containing protein - p	—	OG7 LdBPK_080820.1 ↔ LdBPK_365870.1	OG7
LINF_320027600 ⚠ hypothetical protein - conserved	—	OG7 LdBPK_070810.1 ↔ LdBPK_365870.1	OG7
LINF_040008400 ⚠ mitochondrial exoribonuclease DSS-1 - putativ	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
LINF_280009200 ⚠ rrp44p homologue - putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
LINF_120007900 ornithine decarboxylase - putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_365870.1 OG7 LdBPK_120105.1 ↔ LdBPK_365870.1	Both
LINF_250009300 Translation initiation factor SUI1 - putative	—	OG6 LdBPK_250420.1 ↔ LdBPK_365870.1 OG7 LdBPK_250420.1 ↔ LdBPK_365870.1	Both
LINF_300012500 ⚠ co-chaperone GrpE - putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_004705	Both
LINF_110007000 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LINF_030014200 ⚠ inorganic pyrophosphatase - putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LINF_320047000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004705	Both
LINF_290011000 ⚠ NF-X1 type zinc finger containing protein - p	—	OG6 LdBPK_290620.1 ↔ LdBPK_365870.1 OG7 LdBPK_290620.1 ↔ LdBPK_365870.1	Both
LINF_190012900 ⚠ ABC transport system ATP-binding protein - pu	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006012 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006012	Both
LINF_350009100 hypothetical protein - conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005084 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005084	Both
LINF_350015200 protein kinase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005149	OG6
LINF_170016800 Mak10 subunit - NatC N(alpha)-terminal acetyl	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008986 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008986	Both
LINF_180014100 cyclosporin 16 - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006217	OG6
LINF_170009800 ⚠ Dihydrouridine synthase (Dus) - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_009102	Both
LINF_180005900 ⚠ alpha glucosidase II subunit - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006141	Both
LINF_250014500 ⚠ protein kinase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007401	Both
LINF_360060900 VHS domain containing protein - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008292 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008292	Both
LINF_350032600 acyl-CoA dehydrogenase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005872 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005872	Both
LINF_350008600 hypothetical protein - conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005080 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005080	Both
LINF_330033000 heat shock protein - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005578	OG6
LINF_140020000 inositol-3-phosphate synthase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007453	Both
LINF_210013900 methionyl-tRNA synthetase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007991	Both
LINF_350013700 hypothetical protein - conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005125 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005125	Both
LINF_330018700 hypothetical protein - conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004910 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004910	Both
LINF_360028800 ⚠ NOL1/NOP2/sun family - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004998	Both
LINF_200021600 tRNA (Uracil-5-)-methyltransferase/Protein-L-	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008409	Both
LINF_250006800 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005414	Both
LINF_140019600 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010621	Both
LINF_290005500 ⚠ tryptophanyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010724	Both

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