LINF_140020000

inositol-3-phosphate synthase

Leishmania infantum JPCM5 OG6: OG6_100830 OG7: OG7_0006574 191 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 191 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LINF_190012900 ⚠ ABC transport system ATP-binding protein - pu	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LINF_110016000 pyruvate phosphate dikinase - putative	—	OG6 LdBPK_111000.1 ↔ LdBPK_141450.1 OG6 Tb927.10.7110 ↔ Tb927.11.6280 OG7 Tb927.10.7110 ↔ Tb927.11.6280 OG7 LdBPK_111000.1 ↔ LdBPK_141450.1	Both
LINF_040008400 ⚠ mitochondrial exoribonuclease DSS-1 - putativ	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	OG7
LINF_280007900 ⚠ DIS3-like exonuclease - putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 +1 more	Both
LINF_250014500 ⚠ protein kinase - putative	—	OG6 TCSYLVIO_007401 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LINF_280009200 ⚠ rrp44p homologue - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	Both
LINF_030006400 ⚠ ATP-binding cassette protein subfamily F - me	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	OG7
LINF_230006100 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LINF_350051300 hypothetical protein - conserved	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007453 OG6 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007453	Both
LINF_330008900 ⚠ ATP-binding cassette sub-family F member 1 -	—	OG6 LdBPK_141450.1 ↔ LdBPK_330340.1 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LINF_330022300 ⚠ protein kinase - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LINF_170016500 Phosphorylated CTD interacting factor 1 WW do	—	OG6 LdBPK_141450.1 ↔ LdBPK_171050.1 OG7 LdBPK_141450.1 ↔ LdBPK_171050.1	Both
LINF_120007900 ornithine decarboxylase - putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_141450.1 OG7 LdBPK_120105.1 ↔ LdBPK_141450.1	Both
LINF_110007000 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LINF_030014200 ⚠ inorganic pyrophosphatase - putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LINF_320047000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007453	Both
LINF_360066000 isoleucyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007453	Both
LINF_050013400 hypothetical protein - conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007453	Both
LINF_220021600 alanyl-tRNA synthetase - putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007453	Both
LINF_250006800 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007453	Both
LINF_360005700 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LINF_270032100 ⚠ TPR-repeat protein - putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LINF_360028800 ⚠ NOL1/NOP2/sun family - putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LINF_290033200 ⚠ NOL1/NOP2/sun family/FtsJ-like methyltransfer	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LINF_290028800 UDP-glucose:Glycoprotein Glucosyltransferase	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007453	Both
LINF_350009100 hypothetical protein - conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_007453	Both
LINF_220018500 ⚠ translation initiation factor IF-2 - putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007453	Both
LINF_250009300 Translation initiation factor SUI1 - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_250420.1 OG7 LdBPK_141450.1 ↔ LdBPK_250420.1	Both
LINF_300009800 hypothetical protein - conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_300480.1 OG7 LdBPK_141450.1 ↔ LdBPK_300480.1	Both
LINF_360065600 adenylyl cyclase-associated protein - putativ	—	OG6 LdBPK_141450.1 ↔ LdBPK_365830.1 OG7 LdBPK_141450.1 ↔ LdBPK_365830.1	Both
LINF_020012400 ⚠ Heat shock protein 100 kDa	—	OG6 LdBPK_141450.1 ↔ LdBPK_291360.1 OG7 LdBPK_141450.1 ↔ LdBPK_291360.1	Both
LINF_300025500 calpain-like cysteine peptidase - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_302040.1	OG6
LINF_200022100 ⚠ amidohydrolase - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LINF_290018300 ⚠ Hsp70 protein/TPR repeat/Tetratricopeptide re	—	OG6 LdBPK_141450.1 ↔ LdBPK_291330.1 OG7 LdBPK_141450.1 ↔ LdBPK_291330.1	Both
LINF_250016400 hypothetical protein - conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_251070.1 OG7 LdBPK_141450.1 ↔ LdBPK_251070.1	Both
LINF_120015400 ⚠ N-acyl-L-amino acid amidohydrolase	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LINF_300036300 tRNA (Guanine-1)-methyltransferase - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_303110.1 OG7 LdBPK_141450.1 ↔ LdBPK_303110.1	Both
LINF_260016600 ⚠ RNA pseudouridylate synthase - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_261140.1 OG7 LdBPK_141450.1 ↔ LdBPK_261140.1	Both
LINF_230018400 hypothetical protein - conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_231180.1 OG7 LdBPK_141450.1 ↔ LdBPK_231180.1	Both
LINF_350012100 proteasome activator protein pa26 - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_350770.1 OG7 LdBPK_141450.1 ↔ LdBPK_350770.1	Both
LINF_340048400 ⚠ ubiquitin hydrolase - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_343890.1 OG7 LdBPK_141450.1 ↔ LdBPK_343890.1	Both
LINF_170020400 Methyltransferase domain containing protein -	—	OG6 LdBPK_141450.1 ↔ LdBPK_171410.1 OG7 LdBPK_141450.1 ↔ LdBPK_171410.1	Both
LINF_340018200 hypothetical protein - conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_341230.1 OG7 LdBPK_141450.1 ↔ LdBPK_341230.1	Both
LINF_200022000 ⚠ amidohydrolase - putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LINF_300038100 ⚠ glutamyl-tRNA synthetase - putative	—	OG7 Tb927.10.7110 ↔ Tb927.9.5210	OG7
LINF_290018600 ⚠ Heat shock protein 100 kDa	—	OG6 LdBPK_141450.1 ↔ LdBPK_291360.1 OG7 LdBPK_141450.1 ↔ LdBPK_291360.1	Both
LINF_350028000 ATP-dependent RNA helicase-like protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_352320.1	OG6
LINF_240006100 ankyrin/TPR repeat protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_240130.1	OG6
LINF_240025000 ⚠ cyclin 10	—	OG6 LdBPK_141450.1 ↔ LdBPK_241960.1 OG7 LdBPK_141450.1 ↔ LdBPK_241960.1	Both
LINF_360036200 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_141450.1 ↔ LdBPK_241120.1	OG6

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