LINF_140020000

inositol-3-phosphate synthase
Leishmania infantum JPCM5 OG6: OG6_100830 OG7: OG7_0006574 191 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 191 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— Both
LINF_110016000
pyruvate phosphate dikinase - putative
— Both
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_280007900 ⚠
DIS3-like exonuclease - putative
— +1 more Both
LINF_250014500 ⚠
protein kinase - putative
— Both
LINF_280009200 ⚠
rrp44p homologue - putative
— Both
LINF_030006400 ⚠
ATP-binding cassette protein subfamily F - me
— OG7
LINF_230006100
GDP-mannose pyrophosphorylase
— Both
LINF_350051300
hypothetical protein - conserved
— Both
LINF_330008900 ⚠
ATP-binding cassette sub-family F member 1 -
— Both
LINF_330022300 ⚠
protein kinase - putative
— Both
LINF_170016500
Phosphorylated CTD interacting factor 1 WW do
— Both
LINF_120007900
ornithine decarboxylase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_320047000
Gar1/Naf1 RNA binding region containing prote
— Both
LINF_360066000
isoleucyl-tRNA synthetase - putative
— Both
LINF_050013400
hypothetical protein - conserved
— Both
LINF_220021600
alanyl-tRNA synthetase - putative
— Both
LINF_250006800 ⚠
cleavage and polyadenylation specificity fact
— Both
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_270032100 ⚠
TPR-repeat protein - putative
— OG6
LINF_360028800 ⚠
NOL1/NOP2/sun family - putative
— Both
LINF_290033200 ⚠
NOL1/NOP2/sun family/FtsJ-like methyltransfer
— Both
LINF_290028800
UDP-glucose:Glycoprotein Glucosyltransferase
— Both
LINF_350009100
hypothetical protein - conserved
— Both
LINF_220018500 ⚠
translation initiation factor IF-2 - putative
— Both
LINF_250009300
Translation initiation factor SUI1 - putative
— Both
LINF_300009800
hypothetical protein - conserved
— Both
LINF_360065600
adenylyl cyclase-associated protein - putativ
— Both
LINF_020012400 ⚠
Heat shock protein 100 kDa
— Both
LINF_300025500
calpain-like cysteine peptidase - putative
— OG6
LINF_200022100 ⚠
amidohydrolase - putative
— Both
LINF_290018300 ⚠
Hsp70 protein/TPR repeat/Tetratricopeptide re
— Both
LINF_250016400
hypothetical protein - conserved
— Both
LINF_120015400 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LINF_300036300
tRNA (Guanine-1)-methyltransferase - putative
— Both
LINF_260016600 ⚠
RNA pseudouridylate synthase - putative
— Both
LINF_230018400
hypothetical protein - conserved
— Both
LINF_350012100
proteasome activator protein pa26 - putative
— Both
LINF_340048400 ⚠
ubiquitin hydrolase - putative
— Both
LINF_170020400
Methyltransferase domain containing protein -
— Both
LINF_340018200
hypothetical protein - conserved
— Both
LINF_200022000 ⚠
amidohydrolase - putative
— Both
LINF_300038100 ⚠
glutamyl-tRNA synthetase - putative
— OG7
LINF_290018600 ⚠
Heat shock protein 100 kDa
— Both
LINF_350028000
ATP-dependent RNA helicase-like protein
— OG6
LINF_240006100
ankyrin/TPR repeat protein
— OG6
LINF_240025000 ⚠
cyclin 10
— Both
LINF_360036200 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.