LINF_110007000

acidocalcisomal pyrophosphatase
Leishmania infantum JPCM5 OG6: OG6_100346 OG7: OG7_0003350 284 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 284 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
LINF_350005300 ⚠
pyruvate kinase
— Both
LINF_350005200 ⚠
pyruvate kinase
— Both
LINF_350005400 ⚠
pyruvate kinase
— Both
LINF_080007200 ⚠
ubiquitin-activating enzyme-like protein
— Both
LINF_200016800 ⚠
cysteine peptidase - Clan CA - family C2 - pu
— OG6
LINF_040009500 ⚠
cysteine peptidase - Clan CA - family C2 - pu
— OG6
LINF_230006100 ⚠
GDP-mannose pyrophosphorylase
— Both
LINF_200016900 ⚠
cysteine peptidase - Clan CA - family C2 - pu
— OG6
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— Both
LINF_210027500 ⚠
ATP synthase F1 subunit gamma protein - putat
— Both
LINF_350028700 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_320044700 ⚠
Methyltransferase TYW3 - putative
— OG7
LINF_080013100 ⚠
hypothetical protein - conserved
— OG7
LINF_330034900 ⚠
metallo-peptidase - Clan MF - Family M17
— OG7
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_240026400 ⚠
tubulin folding cofactor D - putative
— Both
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— Both
LINF_300028600 ⚠
SET domain containing protein - putative
— Both
LINF_350009100 ⚠
hypothetical protein - conserved
— Both
LINF_350015200 ⚠
protein kinase - putative
— OG6
LINF_330005900 ⚠
hypothetical protein - conserved
— Both
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— Both
LINF_300011200 ⚠
nitrate reductase - putative
— OG6
LINF_300038700 ⚠
UV excision repair RAD23-like protein
— Both
LINF_330027700 ⚠
ribosome assembly protein RRB1 - putative
— Both
LINF_350011600 ⚠
vacuolar ATP synthase subunit d - putative
— Both
LINF_180014100 ⚠
cyclosporin 16 - putative
— OG6
LINF_350019000 ⚠
threonyl-tRNA synthetase - putative
— Both
LINF_170009800 ⚠
Dihydrouridine synthase (Dus) - putative
— Both
LINF_260029200 ⚠
Zn-finger in Ran binding protein and others/S
— Both
LINF_270030600 ⚠
protein phosphatase-like protein
— OG6
LINF_340045100 ⚠
hypothetical protein - conserved
— Both
LINF_340048700 ⚠
GRIP domain containing protein - putative
— Both
LINF_320007200 ⚠
Histone chaperone Rttp106-like - putative
— Both
LINF_350047400 ⚠
Protein of unknown function (DUF2009) - putat
— Both
LINF_180005900 ⚠
alpha glucosidase II subunit - putative
— Both
LINF_200011400 ⚠
hypothetical protein - conserved
— Both
LINF_320022600 ⚠
protein phosphatase 2C - putative
— OG6
LINF_250027000 ⚠
2 -4-dihydroxyhept-2-ene-1 -7-dioic acid aldo
— Both
LINF_360031600 ⚠
dipeptidyl-peptidase 8-like serine peptidase
— Both
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_350039100 ⚠
hypothetical protein - conserved
— Both
LINF_340050700 ⚠
nucleolar protein family a - putative
— Both
LINF_350016700 ⚠
NADH-dependent fumarate reductase - putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.