LINF_350005400

pyruvate kinase
Leishmania infantum JPCM5 OG6: OG6_100258 OG7: OG7_0002165 189 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 189 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_140018300 ⚠
YjeF-related protein N-terminus/Carbohydrate
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_340040800 ⚠
aldose 1-epimerase-like protein
— Both
LINF_070013900 ⚠
flavoprotein subunit-like protein
— Both
LINF_010009800 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_150022500 ⚠
glutaminyl-tRNA synthetase - putative
— Both
LINF_140006200 ⚠
inosine-guanine nucleoside hydrolase - putati
— Both
LINF_010010100 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_130016900 ⚠
adenylosuccinate synthetase - putative
— Both
LINF_300041000 ⚠
S-adenosylmethionine synthetase
— Both
LINF_010010000 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_200016800 ⚠
cysteine peptidase - Clan CA - family C2 - pu
— OG6
LINF_040009500 ⚠
cysteine peptidase - Clan CA - family C2 - pu
— OG6
LINF_300035200 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_110011900 ⚠
aminopeptidase - putative
— Both
LINF_150023000 ⚠
cAMP specific phosphodiesterase - putative
— Both
LINF_150022900 ⚠
cAMP specific phosphodiesterase - putative
— Both
LINF_290014000 ⚠
guanine deaminase - putative
— Both
LINF_010010200 ⚠
fatty acyl CoA synthetase 2 - putative
— Both
LINF_350016700 ⚠
NADH-dependent fumarate reductase - putative
— Both
LINF_300040800 ⚠
S-adenosylmethionine synthetase
— Both
LINF_240026800 ⚠
transketolase
— Both
LINF_110012000 ⚠
aminopeptidase - putative
— Both
LINF_300035100 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_200016900 ⚠
cysteine peptidase - Clan CA - family C2 - pu
— OG6
LINF_300020600 ⚠
pseudouridine synthase A-like protein - putat
— Both
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— Both
LINF_060014300 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
LINF_340045400 ⚠
phosphomannomutase-like protein
— Both
LINF_320005800 ⚠
N-myristoyl transferase - putative
— Both
LINF_310017700 ⚠
amidohydrolase - putative
— Both
LINF_300019400 ⚠
amidohydrolase - putative
— Both
LINF_200022200 ⚠
amidohydrolase - putative
— Both
LINF_280027300 ⚠
Telomere recombination/Putative GTP-binding c
— Both
LINF_200022100 ⚠
amidohydrolase - putative
— Both
LINF_120015400 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LINF_200022000 ⚠
amidohydrolase - putative
— Both
LINF_310006400 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— Both
LINF_010007100 ⚠
cyclophilin 12 - putative
— OG6
LINF_330017000 ⚠
nicotinate phosphoribosyltransferase - putati
— Both
LINF_330037400 ⚠
transcription elongation factor-like protein
— Both
LINF_120010600 ⚠
glucose-6-phosphate isomerase
— Both
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— Both
LINF_060016500 ⚠
deoxyribose-phosphate aldolase - putative
— Both
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_290027900 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.