LINF_330017000

nicotinate phosphoribosyltransferase - putative
Leishmania infantum JPCM5 OG6: OG6_109462 OG7: OG7_0015320 167 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 167 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_350048600 ⚠
hypothetical protein - conserved
— OG7
LINF_100011600
mitogen-activated protein kinase 3 - putative
— OG6
LINF_360044400 ⚠
Protein of unknown function (DUF2009) - putat
— Both
LINF_320033200 ⚠
superoxide dismutase - putative
— Both
LINF_320022600 ⚠
protein phosphatase 2C - putative
— OG6
LINF_250027000
2 -4-dihydroxyhept-2-ene-1 -7-dioic acid aldo
— Both
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_200011400 ⚠
hypothetical protein - conserved
— Both
LINF_320024000 ⚠
iron superoxide dismutase - putative
— Both
LINF_180011700 ⚠
serine/threonine kinase-like protein - putati
— Both
LINF_310016800
biotin/lipoate protein ligase-like protein
— Both
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— Both
LINF_270018900 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_120005100
PITH domain-containing protein
— Both
LINF_070015200 ⚠
serine/threonine kinase - putative
— Both
LINF_160011100
dihydroorotase - putative
— Both
LINF_260032900
6-phosphogluconolactonase
— Both
LINF_360011200 ⚠
Elongation factor G1 - mitochondrial - putati
— Both
LINF_350047400 ⚠
Protein of unknown function (DUF2009) - putat
— Both
LINF_270030600 ⚠
protein phosphatase-like protein
— OG6
LINF_350005200 ⚠
pyruvate kinase
— Both
LINF_260029200
Zn-finger in Ran binding protein and others/S
— Both
LINF_330005900
hypothetical protein - conserved
— Both
LINF_350005300 ⚠
pyruvate kinase
— Both
LINF_280005500
hypothetical protein - conserved
— Both
LINF_330037400 ⚠
transcription elongation factor-like protein
— Both
LINF_230023300
Ran-binding protein - putative
— Both
LINF_340011000
Gamma-soluble NSF attachment protein (SNAP-ga
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_080013100
hypothetical protein - conserved
— OG7
LINF_270025200 ⚠
GTP binding protein - putative
— OG7
LINF_320038700 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LINF_270032300 ⚠
aldo-keto reductase-like protein
— OG7
LINF_310037500 ⚠
aldehyde reductase - putative
— OG7
LINF_270033890
hypothetical protein - conserved
— OG7
LINF_340047500 ⚠
AP-1 adapter complex gamma subunit - putative
— OG7
LINF_070005500 ⚠
alpha-adaptin-like protein
— OG7
LINF_060010700 ⚠
U-box domain containing protein - putative
— OG7
LINF_190021300 ⚠
eukaryotic translation initiation factor-like
— OG7
LINF_280032200 ⚠
eukaryotic translation initiation factor 4E -
— OG7
LINF_220014000 ⚠
serine/threonine protein kinase sos2 - putati
— OG7
LINF_210005500 ⚠
hypothetical protein - conserved
— OG7
LINF_210027200 ⚠
RNA polymerase II - putative
— OG7
LINF_330025600 ⚠
protein kinase - putative
— OG7
LINF_130012200 ⚠
ubiquitin-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.