LINF_010010200

fatty acyl CoA synthetase 2 - putative
Leishmania infantum JPCM5 OG6: OG6_100746 OG7: OG7_0001203 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_300040800 ⚠
S-adenosylmethionine synthetase
— Both
LINF_330035300 ⚠
enoyl-CoA hydratase/Enoyl-CoA isomerase/3- hy
— Both
LINF_260020500 ⚠
trifunctional enzyme alpha subunit - mitochon
— Both
LINF_110017200 ⚠
sterol 14-alpha-demethylase - putative
— Both
LINF_290014000 ⚠
guanine deaminase - putative
— Both
LINF_260021100 ⚠
proline oxidase - mitochondrial precursor-lik
— Both
LINF_140008500 ⚠
threonine synthase - putative
— Both
LINF_290012400 ⚠
Peroxisomal targeting signal 2 receptor
— Both
LINF_350005400 ⚠
pyruvate kinase
— Both
LINF_350005200 ⚠
pyruvate kinase
— Both
LINF_350005300 ⚠
pyruvate kinase
— Both
LINF_300041000 ⚠
S-adenosylmethionine synthetase
— Both
LINF_150022500 ⚠
glutaminyl-tRNA synthetase - putative
— Both
LINF_120010600 ⚠
glucose-6-phosphate isomerase
— Both
LINF_300038100 ⚠
glutamyl-tRNA synthetase - putative
— OG7
LINF_330037900 ⚠
cysteine peptidase - Clan CA - family C51 - p
— OG7
LINF_250031200 ⚠
CHAP domain/Glutathionylspermidine synthase p
— OG7
LINF_230009800 ⚠
trypanothione synthetase - putative
— OG7
LINF_330037600 ⚠
cysteine peptidase - Clan CA - family C51 - p
— OG7
LINF_340041900 ⚠
ruvb-like 1 DNA helicase - putative
— OG7
LINF_250016700 ⚠
hypothetical protein - conserved
— OG7
LINF_320046900 ⚠
cAMP response protein 1 - putative
— OG7
LINF_130006500 ⚠
protein kinase A regulatory subunit
— OG7
LINF_150019400 ⚠
protein kinase - putative
— OG7
LINF_210027400 ⚠
centromere/microtubule binding protein cbf5 -
— Both
LINF_270025600 ⚠
trypanothione synthetase - putative
— Both
LINF_360030600 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
LINF_300035000 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_300035200 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_300035100 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_250020400 ⚠
GTP-binding protein - putative
— Both
LINF_340035100 ⚠
regulatory subunit of protein kinase a-like p
— Both
LINF_320037600 ⚠
leucine-rich repeat protein - putative
— Both
LINF_260025100 ⚠
hypothetical protein - conserved
— OG6
LINF_340032100 ⚠
ruvB-like DNA helicase - putative
— Both
LINF_050006700 ⚠
dihydrolipoamide branched chain transacylase
— Both
LINF_130016900 ⚠
adenylosuccinate synthetase - putative
— Both
LINF_290035800 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LINF_240026800 ⚠
transketolase
— Both
LINF_270015600 ⚠
isovaleryl-coA dehydrogenase - putative
— Both
LINF_180021400 ⚠
nonspecific nucleoside hydrolase
— Both
LINF_140006200 ⚠
inosine-guanine nucleoside hydrolase - putati
— Both
LINF_350023700 ⚠
60S ribosomal protein L5 - putative
— Both
LINF_350023800 ⚠
60S ribosomal protein L5 - putative
— Both
LINF_350023900 ⚠
60S ribosomal protein L5 - putative
— Both
LINF_270027400 ⚠
branched-chain amino acid aminotransferase -
— Both
LINF_350053100 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LINF_040010800 ⚠
spermidine synthase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.