LINF_270025600

trypanothione synthetase - putative
Leishmania infantum JPCM5 OG6: OG6_111169 OG7: OG7_0010828 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_360044500 ⚠
cysteine synthase
— Both
LINF_170008800 ⚠
cystathionine beta-synthase
— Both
LINF_260013200 ⚠
aspartate--ammonia ligase - putative
— Both
LINF_090013900 ⚠
oligopeptidase b
— OG7
LINF_090014600 ⚠
Uncharacterised protein family (UPF0160) - p
— Both
LINF_240012700 ⚠
malic enzyme - putative
— Both
LINF_350028800 ⚠
aminopeptidase P - putative
— Both
LINF_360078300 ⚠
2 -3-bisphosphoglycerate-independent phosphog
— Both
LINF_340006300 ⚠
malate dehydrogenase - putative
— OG7
LINF_190012000 ⚠
glycosomal malate dehydrogenase
— OG7
LINF_340006500 ⚠
malate dehydrogenase - putative
— OG7
LINF_160005200 ⚠
Holliday junction DNA helicase ruvB N-terminu
— OG7
LINF_100005500 ⚠
thymidylate kinase-like protein
— OG7
LINF_320019300 ⚠
RNA guanylyltransferase - putative
— OG7
LINF_360019700 ⚠
adenylate kinase - putative
— OG7
LINF_210020600 ⚠
adenylate kinase - putative
— OG7
LINF_330022100 ⚠
mitogen activated protein kinase - putative
— OG6
LINF_210023000 ⚠
Cytochrome b5-like Heme/Steroid binding domai
— OG7
LINF_040009650 ⚠
hypothetical protein - conserved
— OG7
LINF_060008700 ⚠
serine peptidase - clan SC - family S9A-like
— OG7
LINF_360065300 ⚠
aminopeptidase P1 - putative
— OG7
LINF_160005000 ⚠
anti-silencing protein a-like protein
— OG7
LINF_190014600 ⚠
CAP-Gly domain containing protein - putative
— OG7
LINF_040014600 ⚠
adenylate kinase - putative
— OG7
LINF_110008400 ⚠
14-3-3 protein 2 - putative
— OG7
LINF_360040400 ⚠
14-3-3 protein 1 - putative
— OG7
LINF_010010400 ⚠
long-chain-fatty-acid-CoA ligase - putative
— OG7
LINF_330031600 ⚠
glycosyl hydrolase-like protein
— OG7
LINF_250028100 ⚠
KIF-1 binding protein C terminal - putative
— OG7
LINF_270025400
paraflagellar rod protein 5 - putative
— OG6
LINF_140008500 ⚠
threonine synthase - putative
— Both
LINF_010010300 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_270027400 ⚠
branched-chain amino acid aminotransferase -
— Both
LINF_040010800 ⚠
spermidine synthase
— Both
LINF_010009800 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_290035800 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LINF_010010100 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_010010000 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_010010200 ⚠
fatty acyl CoA synthetase 2 - putative
— Both
LINF_060011200 ⚠
deoxyuridine triphosphatase - putative
— Both
LINF_300018100 ⚠
pyridoxal kinase - putative
— Both
LINF_280036800 ⚠
cytosolic malate dehydrogenase
— Both
LINF_290014000 ⚠
guanine deaminase - putative
— Both
LINF_340006400 ⚠
malate dehydrogenase
— Both
LINF_340006600 ⚠
mitochondrial malate dehydrogenase
— Both
LINF_270027600 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LINF_220019000 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LINF_230010700 ⚠
acetyl-CoA synthetase - putative
— Both
LINF_230014800 ⚠
acetyl-CoA synthetase - putative
— Both
LINF_360079300 ⚠
serine peptidase clan SC - family S9A - putat
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.