LINF_040010800

spermidine synthase
Leishmania infantum JPCM5 OG6: OG6_100634 OG7: OG7_0003460 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_340006500 ⚠
malate dehydrogenase - putative
— OG7
LINF_190012000 ⚠
glycosomal malate dehydrogenase
— OG7
LINF_340006300 ⚠
malate dehydrogenase - putative
— OG7
LINF_340006600 ⚠
mitochondrial malate dehydrogenase
— Both
LINF_340006400 ⚠
malate dehydrogenase
— Both
LINF_170008800 ⚠
cystathionine beta-synthase
— Both
LINF_360078300
2 -3-bisphosphoglycerate-independent phosphog
— Both
LINF_280026200
ribose 5-phosphate isomerase - putative
— Both
LINF_360044500 ⚠
cysteine synthase
— OG6
LINF_220022300 ⚠
ser/thr protein phosphatase - putative
— OG7
LINF_340021300 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LINF_340021200 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LINF_340021100 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LINF_140008500
threonine synthase - putative
— Both
LINF_220019000 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LINF_270027600 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LINF_010010200 ⚠
fatty acyl CoA synthetase 2 - putative
— Both
LINF_010010400 ⚠
long-chain-fatty-acid-CoA ligase - putative
— OG7
LINF_010010100 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_290008000 ⚠
hypothetical protein - conserved
— OG7
LINF_150008400 ⚠
inhibitor of serine peptidase (ISP) - putativ
— OG7
LINF_280021300 ⚠
ATP-dependent RNA helicase FAL1 - putative
— OG7
LINF_130011700 ⚠
Metallopeptidase family M24 - putative
— OG7
LINF_010012800 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_010012900 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_350008800 ⚠
ATP-dependent DEAD-box RNA helicase - putativ
— OG7
LINF_150012400 ⚠
ecotin - putative
— OG7
LINF_330037900 ⚠
cysteine peptidase - Clan CA - family C51 - p
— OG7
LINF_250031200 ⚠
CHAP domain/Glutathionylspermidine synthase p
— OG7
LINF_230009800 ⚠
trypanothione synthetase - putative
— OG7
LINF_330037600 ⚠
cysteine peptidase - Clan CA - family C51 - p
— OG7
LINF_360053800 ⚠
mitochondrial intermediate peptidase - putati
— OG7
LINF_360077400
y113g7b.23 protein-like protein
— Both
LINF_270025600 ⚠
trypanothione synthetase - putative
— Both
LINF_320015200
ubiquitin-conjugating enzyme protein - putati
— Both
LINF_060011200
deoxyuridine triphosphatase - putative
— Both
LINF_280036800
cytosolic malate dehydrogenase
— Both
LINF_260011300
hypothetical protein - conserved
— Both
LINF_340016700 ⚠
uracil phosphoribosyltransferase - putative
— Both
LINF_310033000 ⚠
uridine kinase-like protein
— Both
LINF_290035800
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LINF_190006400 ⚠
metallo-peptidase - Clan MG - Family M24
— Both
LINF_330034400
UDP-N-acetylglucosamine pyrophosphorylase - p
— Both
LINF_150012500 ⚠
ecotin - putative
— Both
LINF_170012100 ⚠
bis(5'-nucleosyl)-tetraphosphatase - symmetri
— Both
LINF_220010800 ⚠
peptidyl-prolyl cis-trans isomerase - putativ
— Both
LINF_210024300 ⚠
ATP-dependent RNA helicase SUB2 - putative
— Both
LINF_010010000 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_060017600
protein kinase - putative
— OG6
LINF_060016500
deoxyribose-phosphate aldolase - putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.