LINF_130011700

Metallopeptidase family M24 - putative
Leishmania infantum JPCM5 OG6: OG6_146697 OG7: OG7_0006554 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_010012900 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_110006300 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LINF_220022300 ⚠
ser/thr protein phosphatase - putative
— OG7
LINF_170012100 ⚠
bis(5'-nucleosyl)-tetraphosphatase - symmetri
— OG7
LINF_270033860 ⚠
hypothetical protein (non-ATG)
— OG7
LINF_360053800 ⚠
mitochondrial intermediate peptidase - putati
— OG7
LINF_260020700 ⚠
thimet oligopeptidase - putative
— OG7
LINF_340006500 ⚠
malate dehydrogenase - putative
— OG7
LINF_360077400 ⚠
y113g7b.23 protein-like protein
— OG7
LINF_350008800 ⚠
ATP-dependent DEAD-box RNA helicase - putativ
— OG7
LINF_340006300 ⚠
malate dehydrogenase - putative
— OG7
LINF_130011800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_220010800 ⚠
peptidyl-prolyl cis-trans isomerase - putativ
— OG7
LINF_210024300 ⚠
ATP-dependent RNA helicase SUB2 - putative
— OG7
LINF_010012800 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_360010900 ⚠
ubiquitin-like protein - putative
— OG7
LINF_330034400 ⚠
UDP-N-acetylglucosamine pyrophosphorylase - p
— OG7
LINF_280021300 ⚠
ATP-dependent RNA helicase FAL1 - putative
— OG7
LINF_340006400 ⚠
malate dehydrogenase
— OG7
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— OG7
LINF_190012000 ⚠
glycosomal malate dehydrogenase
— OG7
LINF_350057700 ⚠
GTP-binding protein - putative
— OG7
LINF_270021500 ⚠
proteasome regulatory non-ATP-ase subunit 3 -
— OG7
LINF_150012400 ⚠
ecotin - putative
— OG7
LINF_150012500 ⚠
ecotin - putative
— OG7
LINF_150008400 ⚠
inhibitor of serine peptidase (ISP) - putativ
— OG7
LINF_320021300 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_360082400 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_180007300 ⚠
60S ribosomal protein L7 - putative
— OG7
LINF_260018700 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LINF_350055500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_050009600 ⚠
GTPase - putative
— OG7
LINF_290008000 ⚠
hypothetical protein - conserved
— OG7
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— OG7
LINF_330033100 ⚠
ras-like small GTPases - putative
— OG7
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— OG7
LINF_100006100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_350014200 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LINF_360037400 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LINF_290017100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_340047100 ⚠
target of rapamycin kinase 3
— OG7
LINF_040012600 ⚠
60S ribosomal protein L10 - putative
— Both
LINF_040014500 ⚠
60S ribosomal protein L10 - putative
— Both
LINF_230005500 ⚠
cyclophilin 11 - putative
— OG6
LINF_290007700 ⚠
hypothetical protein - conserved
— Both
LINF_320038800 ⚠
ribosomal protein L3 - putative
— Both
LINF_330024700 ⚠
cyclophilin 4 - putative
— OG6
LINF_070010500 ⚠
60S ribosomal protein L7a - putative
— Both
LINF_340019700 ⚠
mitochondrial DNA polymerase I protein A - pu
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.