LINF_010012800

eukaryotic initiation factor 4a - putative
Leishmania infantum JPCM5 OG6: OG6_101294 OG7: OG7_0000130 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_340006400 ⚠
malate dehydrogenase
— OG7
LINF_230005400 ⚠
peroxidoxin
— OG7
LINF_150018800 ⚠
tryparedoxin peroxidase
— OG7
LINF_040010800 ⚠
spermidine synthase
— OG7
LINF_190006400 ⚠
metallo-peptidase - Clan MG - Family M24
— OG7
LINF_130011700 ⚠
Metallopeptidase family M24 - putative
— OG7
LINF_260020700 ⚠
thimet oligopeptidase - putative
— OG7
LINF_360053800 ⚠
mitochondrial intermediate peptidase - putati
— OG7
LINF_270033860 ⚠
hypothetical protein (non-ATG)
— OG7
LINF_340006600 ⚠
mitochondrial malate dehydrogenase
— OG7
LINF_290008000 ⚠
hypothetical protein - conserved
— OG7
LINF_190012000 ⚠
glycosomal malate dehydrogenase
— OG7
LINF_150018600 ⚠
tryparedoxin peroxidase
— OG7
LINF_330034400 ⚠
UDP-N-acetylglucosamine pyrophosphorylase - p
— OG7
LINF_220010800 ⚠
peptidyl-prolyl cis-trans isomerase - putativ
— OG7
LINF_340006300 ⚠
malate dehydrogenase - putative
— OG7
LINF_360077400 ⚠
y113g7b.23 protein-like protein
— OG7
LINF_300041400 ⚠
mago nashi-like protein - putative
— OG7
LINF_340006500 ⚠
malate dehydrogenase - putative
— OG7
LINF_170012100 ⚠
bis(5'-nucleosyl)-tetraphosphatase - symmetri
— OG7
LINF_220022300 ⚠
ser/thr protein phosphatase - putative
— OG7
LINF_150008400 ⚠
inhibitor of serine peptidase (ISP) - putativ
— OG7
LINF_150012500 ⚠
ecotin - putative
— OG7
LINF_150012400 ⚠
ecotin - putative
— OG7
LINF_070015200 ⚠
serine/threonine kinase - putative
— OG7
LINF_320044000 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase - pu
— Both
LINF_340041600 ⚠
amidinotransferase - putative
— Both
LINF_310016800 ⚠
biotin/lipoate protein ligase-like protein
— Both
LINF_180007000 ⚠
UDP-galactopyranose mutase
— Both
LINF_180009600 ⚠
tubulin-specific chaperone - putative
— OG7
LINF_190014600 ⚠
CAP-Gly domain containing protein - putative
— OG7
LINF_060016500 ⚠
deoxyribose-phosphate aldolase - putative
— OG7
LINF_240027300 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase - put
— OG7
LINF_070007100 ⚠
protein phosphatase 2A - regulatory subunit B
— OG7
LINF_280026600 ⚠
protein kinase - putative
— OG7
LINF_180011700 ⚠
serine/threonine kinase-like protein - putati
— OG7
LINF_300012900 ⚠
4-methyl-5(beta-hydroxyethyl)-thiazole monoph
— Both
LINF_320043800 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LINF_210006900 ⚠
serine/threonine-protein kinase-like protein
— OG7
LINF_360014700 ⚠
SNF1-related protein kinases - putative
— OG7
LINF_330025600 ⚠
protein kinase - putative
— OG7
LINF_320043700 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LINF_220014000 ⚠
serine/threonine protein kinase sos2 - putati
— OG7
LINF_290027900 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LINF_320043900 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LINF_150019000 ⚠
tryparedoxin peroxidase
— OG7
LINF_250020400 ⚠
GTP-binding protein - putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.