LINF_320043900

3-hydroxyisobutyryl-coenzyme a hydrolase-like protein
Leishmania infantum JPCM5 OG6: OG6_138999 OG7: OG7_0000750 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_160013000 ⚠
transaldolase - putative
— OG7
LINF_340041600 ⚠
amidinotransferase - putative
— OG7
LINF_210024300 ⚠
ATP-dependent RNA helicase SUB2 - putative
— OG7
LINF_010012900 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_350008800 ⚠
ATP-dependent DEAD-box RNA helicase - putativ
— OG7
LINF_230025500 ⚠
alanine racemase - putative
— OG7
LINF_260029200 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
LINF_270032300 ⚠
aldo-keto reductase-like protein
— OG7
LINF_260017100 ⚠
aldo/keto reductase - putative
— OG7
LINF_310037500 ⚠
aldehyde reductase - putative
— OG7
LINF_330014200 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_320021600 ⚠
phosphomannose isomerase
— OG7
LINF_340047500 ⚠
AP-1 adapter complex gamma subunit - putative
— OG7
LINF_070005500 ⚠
alpha-adaptin-like protein
— OG7
LINF_250028300 ⚠
succinyl-CoA synthetase alpha subunit - putat
— OG7
LINF_300014500 ⚠
adenosine kinase-like protein
— OG7
LINF_250028400 ⚠
succinyl-CoA synthetase alpha subunit - putat
— OG7
LINF_300014400 ⚠
adenosine kinase - putative
— OG7
LINF_340043400 ⚠
adenosine kinase-like protein
— OG7
LINF_320015200 ⚠
ubiquitin-conjugating enzyme protein - putati
— OG7
LINF_190021800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LINF_290019000 ⚠
carnitine/choline acetyltransferase - putativ
— OG7
LINF_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LINF_320014700 ⚠
Alpha/beta hydrolase family - putative
— OG7
LINF_310006400 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_320030400 ⚠
hypothetical protein
— OG7
LINF_340045400 ⚠
phosphomannomutase-like protein
— OG7
LINF_320030500 ⚠
hypothetical protein - conserved
— OG7
LINF_210015000 ⚠
xanthine phosphoribosyltransferase
— OG7
LINF_210014900 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— OG7
LINF_250016200 ⚠
dehydrogenase-like protein
— OG7
LINF_300006800 ⚠
2-hydroxy-3-oxopropionate reductase - putativ
— OG7
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— OG7
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— OG7
LINF_310036800 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LINF_290028700 ⚠
Domain of unknown function (DUF4139) - putati
— OG7
LINF_260024400 ⚠
deoxyhypusine hydroxylase - putative
— OG7
LINF_160019200 ⚠
hypothetical protein - conserved
— OG7
LINF_030012600 ⚠
hypothetical protein - conserved
— OG7
LINF_360037500 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain
— OG7
LINF_310023400 ⚠
diphthine synthase-like protein
— OG7
LINF_240008500 ⚠
aspartate aminotransferase - putative
— OG7
LINF_010007000 ⚠
UBA/TS-N domain/CUE domain/Domain of unknown
— OG7
LINF_360078300 ⚠
2 -3-bisphosphoglycerate-independent phosphog
— OG7
LINF_280016800 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_240006800 ⚠
transcription elongation factor - putative
— OG7
LINF_330037400 ⚠
transcription elongation factor-like protein
— OG7
LINF_220008400 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LINF_350012900 ⚠
aspartate aminotransferase - putative
— OG7
LINF_330017000 ⚠
nicotinate phosphoribosyltransferase - putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.