LINF_300006800

2-hydroxy-3-oxopropionate reductase - putative
Leishmania infantum JPCM5 OG6: OG6_101839 OG7: OG7_0002731 223 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 223 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_130012200 ⚠
ubiquitin-like protein
— Both
LINF_360010900 ⚠
ubiquitin-like protein - putative
— OG7
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— Both
LINF_160006700 ⚠
50S ribosomal protein L17 - putative
— OG7
LINF_280026600 ⚠
protein kinase - putative
— OG7
LINF_350041000 ⚠
CRAL/TRIO - N-terminal domain/CRAL/TRIO domai
— OG7
LINF_310023900 ⚠
MYND finger containing protein - putative
— OG7
LINF_320031200 ⚠
Cid1 family poly A polymerase - putative
— OG7
LINF_360041200 ⚠
Enoyl-CoA hydratase/isomerase family/2-enoyl-
— OG7
LINF_330034300 ⚠
mitochondrial RNA binding complex 1 subunit
— OG7
LINF_270016600 ⚠
hypothetical protein - conserved
— OG7
LINF_210025900 ⚠
mitochondrial RNA binding complex 1 subunit -
— OG7
LINF_030005400 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LINF_310037500 ⚠
aldehyde reductase - putative
— OG7
LINF_270032300 ⚠
aldo-keto reductase-like protein
— OG7
LINF_270025900 ⚠
hypothetical protein - conserved
— OG7
LINF_320028300 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
LINF_360007000 ⚠
elongation factor 2
— OG7
LINF_360006800 ⚠
elongation factor 2
— OG7
LINF_360006900 ⚠
elongation factor 2
— OG7
LINF_360007100 ⚠
elongation factor 2
— OG7
LINF_080013100 ⚠
hypothetical protein - conserved
— OG7
LINF_030007000 ⚠
hypothetical protein - conserved
— OG7
LINF_260028100 ⚠
hypothetical protein - conserved
— OG7
LINF_300031800 ⚠
hypothetical protein - conserved
— OG7
LINF_350040300 ⚠
hypothetical protein - conserved
— OG7
LINF_040005500 ⚠
hypothetical protein - conserved
— OG7
LINF_050013800 ⚠
hypothetical protein - conserved
— OG7
LINF_150008300 ⚠
hypothetical protein - conserved
— OG7
LINF_200010400 ⚠
hypothetical protein - conserved
— Both
LINF_330006600 ⚠
Protein of unknown function (DUF1762) - putat
— Both
LINF_360068600 ⚠
paraflagellar rod component - putative
— Both
LINF_330008900 ⚠
ATP-binding cassette sub-family F member 1 -
— Both
LINF_360038000 ⚠
ATP-dependent RNA helicase - putative
— Both
LINF_350035900 ⚠
ubiquitin-activating enzyme E1 - putative
— Both
LINF_140015200 ⚠
glutathione synthetase - putative
— Both
LINF_280019500 ⚠
haloacid dehalogenase-like hydrolase - putati
— Both
LINF_240008500 ⚠
aspartate aminotransferase - putative
— Both
LINF_350012900 ⚠
aspartate aminotransferase - putative
— Both
LINF_280016800 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_280017100 ⚠
electron-transfer-flavoprotein - alpha polype
— Both
LINF_230025500 ⚠
alanine racemase - putative
— Both
LINF_220008200 ⚠
SEP domain containing protein - putative
— Both
LINF_360042000 ⚠
hypothetical protein - conserved
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_130006300 ⚠
hypothetical protein - conserved
— OG7
LINF_300021700 ⚠
CRAL/TRIO - N-terminal domain/CRAL/TRIO domai
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.