LINF_350035900

ubiquitin-activating enzyme E1 - putative
Leishmania infantum JPCM5 OG6: OG6_100444 OG7: OG7_0003530 180 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 180 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_150020800 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_340048400 ⚠
ubiquitin hydrolase - putative
— Both
LINF_050013100 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_110012700 ⚠
anion-transporting ATPase-like protein
— Both
LINF_180012600 ⚠
Elongation factor Tu - mitochondrial - putati
— Both
LINF_200012800 ⚠
tubulin-tyrosine ligase - putative
— Both
LINF_140015200 ⚠
glutathione synthetase - putative
— Both
LINF_350028600 ⚠
Importin 1
— Both
LINF_030012700 ⚠
Ubiquitin-like domain containing protein - pu
— Both
LINF_350028300 ⚠
hypothetical protein - conserved
— Both
LINF_280031900 ⚠
MRP protein-like protein
— OG6
LINF_260009300 ⚠
nucleotide binding protein-like protein
— Both
LINF_210012200 ⚠
nucleotide-binding protein - putative
— Both
LINF_340049900 ⚠
hypothetical protein - conserved
— Both
LINF_200010400 ⚠
hypothetical protein - conserved
— Both
LINF_160008200 ⚠
Met-10+ like-protein - putative
— Both
LINF_020008600 ⚠
casein kinase II - alpha chain - putative
— OG6
LINF_330008900 ⚠
ATP-binding cassette sub-family F member 1 -
— Both
LINF_130012700 ⚠
protein kinase - putative
— Both
LINF_210017100 ⚠
Programmed cell death protein 2 - C-terminal
— Both
LINF_220017200 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LINF_220017300 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LINF_020005300 ⚠
aminopeptidase P1 - putative
— Both
LINF_250031600 ⚠
aminopeptidase P1 - putative
— Both
LINF_350012100 ⚠
proteasome activator protein pa26 - putative
— Both
LINF_030012500 ⚠
TatD related DNase - putative
— Both
LINF_050007200 ⚠
hydrogenase - putative
— Both
LINF_070012900 ⚠
HEAT-like repeat - putative
— OG7
LINF_100012500 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LINF_360007100 ⚠
elongation factor 2
— OG7
LINF_360006800 ⚠
elongation factor 2
— OG7
LINF_170008700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_260026100 ⚠
hypothetical protein - conserved
— OG7
LINF_340047400 ⚠
HECT-domain (ubiquitin-transferase) - putativ
— OG7
LINF_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LINF_360053000 ⚠
ubiquitin protein ligase - putative
— OG7
LINF_260012500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_360049700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_310035800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_300028100 ⚠
Leucine Rich repeats (2 copies) - putative
— OG7
LINF_290027300 ⚠
hypothetical protein - conserved
— OG7
LINF_030011900 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LINF_330007100 ⚠
metallo-peptidase - Clan MC - Family M14 - pu
— OG7
LINF_360006900 ⚠
elongation factor 2
— OG7
LINF_360033800 ⚠
cyclin-e binding protein 1-like protein
— OG7
LINF_320021500 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_300012600 ⚠
heat shock protein grpe
— OG7
LINF_220010200 ⚠
Putative tRNA binding domain containing prote
— OG7
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.