LINF_360053000

ubiquitin protein ligase - putative
Leishmania infantum JPCM5 OG6: OG6_478893 OG7: OG7_0002947 161 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 161 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_350038000 ⚠
Peroxin 19
— OG7
LINF_250023700 ⚠
LSM domain containing protein - putative
— OG7
LINF_360049700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_310035800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_010006500 ⚠
LSM domain containing protein - putative
— OG7
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
LINF_320016400 ⚠
small nuclear ribonucleoprotein - putative
— OG7
LINF_350050400 ⚠
sm-f snRNP core complex protein - putative
— OG7
LINF_360033800 ⚠
cyclin-e binding protein 1-like protein
— OG7
LINF_300017700 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LINF_260005000 ⚠
Lsm7p protein - putative
— OG7
LINF_260012400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_110009100 ⚠
chromatin binding protein - putative
— OG7
LINF_170008700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_340025200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_260012500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_150020800 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_340048400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_050015100 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LINF_280024500 ⚠
replication factor A - 51kDa subunit - putati
— OG7
LINF_280026700 ⚠
hypothetical protein - conserved
— OG7
LINF_230012700 ⚠
Galactose oxidase - central domain containing
— OG7
LINF_270015700 ⚠
XRN 5'-3' exonuclease N-terminus - putative
— OG7
LINF_190015800 ⚠
hypothetical protein - conserved
— OG7
LINF_160009000 ⚠
XRN 5'-3' exonuclease N-terminus - putative
— OG7
LINF_340051600 ⚠
sjogren s syndrome nuclear autoantigen 1 - pu
— OG7
LINF_220011900 ⚠
guide RNA associated protein - GAP2 - putativ
— OG7
LINF_050011200 ⚠
Surp module - putative
— OG7
LINF_150018300 ⚠
glutamate dehydrogenase
— OG7
LINF_340033500 ⚠
methyltransferase-like protein
— OG7
LINF_210015700 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG7
LINF_180010500 ⚠
hypothetical protein - conserved
— OG7
LINF_280018000 ⚠
hypothetical protein - conserved
— OG7
LINF_180011800 ⚠
PA26 p53-induced protein (sestrin) - putative
— OG7
LINF_070006000 ⚠
metallo-peptidase - Clan ME - Family M16C
— OG7
LINF_110014900 ⚠
PUB domain containing protein - putative
— OG7
LINF_350033000 ⚠
hypothetical protein - conserved
— OG7
LINF_330031600 ⚠
glycosyl hydrolase-like protein
— OG7
LINF_350053700 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LINF_340033600 ⚠
hypothetical protein - conserved
— OG7
LINF_200014300 ⚠
cyclophilin 15 - putative
— OG7
LINF_260009200 ⚠
pseudouridylate synthase-like protein
— OG7
LINF_340008200 ⚠
tRNA pseudouridine synthase - putative
— OG7
LINF_190015500 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LINF_300010300 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LINF_210012200 ⚠
nucleotide-binding protein - putative
— OG7
LINF_050007200 ⚠
hydrogenase - putative
— OG7
LINF_260009300 ⚠
nucleotide binding protein-like protein
— OG7
LINF_300020600 ⚠
pseudouridine synthase A-like protein - putat
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.