LINF_180011800

PA26 p53-induced protein (sestrin) - putative
Leishmania infantum JPCM5 OG6: OG6_141922 OG7: OG7_0006056 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_340008200 ⚠
tRNA pseudouridine synthase - putative
— OG7
LINF_090009200 ⚠
Ring finger domain/RING-H2 zinc finger contai
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_120008900 ⚠
pumillio protein 4 - putative
— OG7
LINF_200019000 ⚠
pumilio protein 9 - putative
— OG7
LINF_230026400 ⚠
neutral sphingomyelinase activation associate
— OG7
LINF_340047400 ⚠
HECT-domain (ubiquitin-transferase) - putativ
— OG7
LINF_250008600 ⚠
hypothetical protein - conserved
— OG7
LINF_190015500 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LINF_350029800 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_060005400 ⚠
pumilio/PUF RNA binding protein 5 - putative
— OG7
LINF_360037300 ⚠
predicted zinc finger protein
— OG7
LINF_360007500 ⚠
peptidyl-prolyl cis-trans isomerase - putativ
— OG7
LINF_360075700 ⚠
protein transport protein Sec23-like protein
— OG7
LINF_320027600 ⚠
hypothetical protein - conserved
— OG7
LINF_330034900 ⚠
metallo-peptidase - Clan MF - Family M17
— OG7
LINF_120007900
ornithine decarboxylase - putative
— Both
LINF_110017400
hypothetical protein - conserved
— Both
LINF_200014300
cyclophilin 15 - putative
— Both
LINF_180019600 ⚠
pumilio protein 2 - putative
— Both
LINF_270018400 ⚠
RING-H2 zinc finger/Anaphase-promoting comple
— OG7
LINF_260016600 ⚠
RNA pseudouridylate synthase - putative
— OG7
LINF_040007600 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_360023600 ⚠
neurobeachin/beige protein - putative
— OG7
LINF_170005400 ⚠
Anaphase-promoting complex subunit 11 RING-H2
— OG7
LINF_210021100 ⚠
Ring finger domain/RING-H2 zinc finger/Zinc f
— OG7
LINF_220020400 ⚠
fk506-binding protein 1-like protein
— OG7
LINF_100015600 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— Both
LINF_200018900 ⚠
pumilio protein 9 - putative
— OG7
LINF_190014900 ⚠
peptidyl-prolyl cis-trans isomerase - macroph
— OG7
LINF_360005400 ⚠
PUF1 - putative
— OG7
LINF_210026600 ⚠
pumillio protein 3 - putative
— OG7
LINF_190021700 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LINF_230006200 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LINF_220005600 ⚠
transcription factor-like protein
— OG7
LINF_260009200 ⚠
pseudouridylate synthase-like protein
— OG7
LINF_360053000 ⚠
ubiquitin protein ligase - putative
— OG7
LINF_150009000 ⚠
RNA pseudouridylate synthase - putative
— Both
LINF_330019100 ⚠
pumilio protein 6 - putative
— Both
LINF_360066000
isoleucyl-tRNA synthetase - putative
— Both
LINF_190012400
hypothetical protein - conserved
— Both
LINF_320030300
hypothetical protein - conserved
— Both
LINF_290011000 ⚠
NF-X1 type zinc finger containing protein - p
— Both
LINF_240011400 ⚠
Kinesin-13 3 - putative
— Both
LINF_260017800
hypothetical protein - conserved
— Both
LINF_200012400
conserved protein - unknown function
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.