LINF_230026400

neutral sphingomyelinase activation associated factor-like protein
Leishmania infantum JPCM5 OG6: OG6_104527 OG7: OG7_0001358 226 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 226 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_350054700 ⚠
DNA replication licensing factor MCM9 - putat
— OG7
LINF_320024300 ⚠
chaperonin HSP60 - mitochondrial precursor
— OG7
LINF_330026500 ⚠
hypothetical protein - conserved
— OG7
LINF_110016100 ⚠
inositol-1 -4 -5-trisphosphate (IP3) 5-phosph
— OG7
LINF_320012400 ⚠
ubiquitin-conjugating enzyme E2 - putative
— OG7
LINF_360027200 ⚠
chaperonin HSP60 - mitochondrial precursor
— OG7
LINF_340008300 ⚠
hypothetical protein - conserved
— OG7
LINF_360040500 ⚠
hypothetical protein - conserved
— OG7
LINF_040016000 ⚠
hypothetical protein - conserved
— OG7
LINF_360027100 ⚠
chaperonin HSP60 - mitochondrial precursor
— OG7
LINF_300033500 ⚠
chaperonin HSP60/CNP60 - putative
— OG7
LINF_330023100 ⚠
hypothetical protein - conserved
— OG7
LINF_300021100 ⚠
hypothetical protein - conserved
— OG7
LINF_120007900 ⚠
ornithine decarboxylase - putative
— OG7
LINF_110008600 ⚠
hypothetical protein - conserved
— OG7
LINF_160012000 ⚠
hypothetical protein - conserved
— OG7
LINF_220014800 ⚠
hypothetical protein - conserved
— OG7
LINF_210020300 ⚠
hypothetical protein - conserved
— OG7
LINF_230023100 ⚠
DNA polymerase theta (helicase domain only) -
— OG7
LINF_170016300 ⚠
ATP-dependent RNA helicase - putative
— OG7
LINF_320019700 ⚠
ATP-dependent DNA DEAD/DEAH box helicase - pu
— OG7
LINF_130009900 ⚠
ATP-dependent RNA helicase - putative
— OG7
LINF_110015800 ⚠
HIT zinc finger containing protein - putative
— OG7
LINF_340008800 ⚠
Conserved oligomeric complex COG6 - putative
— OG7
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_350016600 ⚠
NADH-dependent fumarate reductase - putative
— OG7
LINF_340034000 ⚠
hypothetical protein - conserved
— OG7
LINF_280014100 ⚠
DNA replication licensing factor MCM2 - putat
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_320039200 ⚠
NADH dehydrogenase subunit NI8M - putative
— OG7
LINF_360027000 ⚠
hypothetical protein - conserved
— OG7
LINF_360038700 ⚠
cullin-like protein
— OG7
LINF_340020700 ⚠
hypothetical protein - conserved
— OG7
LINF_300029800 ⚠
hypothetical protein - conserved
— OG7
LINF_310038500 ⚠
acetyl-CoA carboxylase - putative
— OG7
LINF_300042900 ⚠
CPSF-domain protein - putative
— OG7
LINF_050014100 ⚠
CPSF A subunit region containing protein - pu
— OG7
LINF_070013900 ⚠
flavoprotein subunit-like protein
— OG7
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— OG7
LINF_360051300 ⚠
WD domain - G-beta repeat/Utp21 specific WD40
— OG7
LINF_360035800 ⚠
Flagellar Member 1
— OG7
LINF_310034600 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG7
LINF_160018000 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_250021400 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LINF_350021500 ⚠
hypothetical protein - conserved
— OG7
LINF_360059000 ⚠
2OG-Fe(II) oxygenase superfamily - putative
— OG7
LINF_310018600 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LINF_310026800 ⚠
ubiquitin-fusion protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.