LINF_340034000

hypothetical protein - conserved
Leishmania infantum JPCM5 OG6: OG6_102026 OG7: OG7_0007248 152 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 152 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_300018400
hypothetical protein - conserved
— Both
LINF_190011500 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LINF_290006300 ⚠
RNA polymerase subunit - putative
— Both
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— OG7
LINF_350044000 ⚠
T-complex protein 1 - eta subunit - putative
— +4 more Both
LINF_310018600
Protein of unknown function (DUF3638)/Protein
— Both
LINF_230006200 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LINF_340027800
Glycosyl hydrolase family 65 central catalyti
— Both
LINF_340050900
coatomer alpha subunit - putative
— Both
LINF_360029500
Spc97 / Spc98 family - putative
— Both
LINF_360066800
hypothetical protein - conserved
— Both
LINF_350030100
hypothetical protein - conserved
— Both
LINF_340048900
hypothetical protein - conserved
— Both
LINF_360061900
glycosyl hydrolase - putative
— Both
LINF_360037400 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— Both
LINF_340041500
hypothetical protein - conserved
— Both
LINF_350027800
hypothetical protein - conserved
— Both
LINF_360062100 ⚠
AP-3 complex subunit beta - putative
— Both
LINF_340048700
GRIP domain containing protein - putative
— Both
LINF_360048500
hypothetical protein - conserved
— Both
LINF_360029000
hypothetical protein - conserved
— Both
LINF_200005000 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_310006600 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_080016200 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LINF_330028000 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_360063600 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_360039800 ⚠
Tubulin binding cofactor C - putative
— OG7
LINF_130022100 ⚠
chaperonin TCP20 - putative
— +3 more OG7
LINF_360031500 ⚠
Cullin protein neddylation domain containing
— OG7
LINF_360038700 ⚠
cullin-like protein
— OG7
LINF_240029100 ⚠
cullin-like protein-like protein
— OG7
LINF_280027800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_160018000 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_230026400 ⚠
neutral sphingomyelinase activation associate
— OG7
LINF_330037100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_270019200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_110015900 ⚠
adaptin-related protein-like protein
— OG7
LINF_360079500 ⚠
adaptin complex 1 subunit - putative
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_340047100 ⚠
target of rapamycin kinase 3
— OG7
LINF_320036300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_360019700 ⚠
adenylate kinase - putative
— OG7
LINF_040014600 ⚠
adenylate kinase - putative
— OG7
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— OG7
LINF_350029400 ⚠
ubiquitin hydrolase - putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.