LINF_190011500

DNA-directed RNA polymerases I and III subunit RPAC1 - putative
Leishmania infantum JPCM5 OG6: OG6_102180 OG7: OG7_0003550 109 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 109 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_200005000 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— Both
LINF_300018400 ⚠
hypothetical protein - conserved
— Both
LINF_280027200 ⚠
DNA-directed RNA polymerase-like protein
— Both
LINF_270022300 ⚠
DNA-directed RNA polymerase II-like protein
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— +2 more Both
LINF_250011500 ⚠
RNA polymerase I second largest subunit - put
— OG7
LINF_310006600 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— Both
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— +2 more Both
LINF_340034000 ⚠
hypothetical protein - conserved
— Both
LINF_160019300 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more Both
LINF_290009000 ⚠
RNA polymerase Rpb4 - putative
— OG7
LINF_250012700 ⚠
hypothetical protein - conserved
— OG7
LINF_320019700 ⚠
ATP-dependent DNA DEAD/DEAH box helicase - pu
— OG7
LINF_230023100 ⚠
DNA polymerase theta (helicase domain only) -
— OG7
LINF_130016200 ⚠
DNA-directed RNA polymerase I subunit - putat
— OG7
LINF_250019300 ⚠
RNA polymerase subunit RPB10 - putative
— OG7
LINF_250006500 ⚠
DNA-directed RNA polymerase I subunit - putat
— OG7
LINF_340014700 ⚠
DNA-directed RNA polymerase III subunit - put
— OG7
LINF_160005200 ⚠
Holliday junction DNA helicase ruvB N-terminu
— OG7
LINF_260017600 ⚠
hypothetical protein - conserved
— OG7
LINF_140018100 ⚠
ras-like small GTPases - putative
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_320019300 ⚠
RNA guanylyltransferase - putative
— OG7
LINF_360019700 ⚠
adenylate kinase - putative
— OG7
LINF_350040400 ⚠
zinc finger protein - putative
— OG7
LINF_190015000 ⚠
FYVE zinc finger containing protein - putativ
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_180011100 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LINF_040014600 ⚠
adenylate kinase - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_240019400 ⚠
hypothetical protein - conserved
— OG7
LINF_210016800 ⚠
histone H2A - putative
— OG7
LINF_340018600 ⚠
hypothetical protein - conserved
— OG7
LINF_010010700 ⚠
pre-mRNA processing factor 3 (PRP3)/Protein o
— OG7
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— OG7
LINF_330008900 ⚠
ATP-binding cassette sub-family F member 1 -
— OG7
LINF_200010300 ⚠
DNA-directed RNA polymerase 2 - RPB12 subunit
— OG7
LINF_260016400 ⚠
mitochondrial RNA binding complex 1 subunit -
— OG7
LINF_210021500 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LINF_050009000 ⚠
structural maintenance of chromosome (SMC) -
— OG7
LINF_350040500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LINF_210016900 ⚠
histone H2A - putative
— OG7
LINF_290023900 ⚠
histone H2A - putative
— OG7
LINF_290024100 ⚠
histone H2A - putative
— OG7
LINF_190011200 ⚠
histone H3 variant - putative
— OG7
LINF_090006100 ⚠
calmodulin-like protein containing EF hand do
— OG7
LINF_080005800 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LINF_090018000 ⚠
DNA-directed RNA polymerase III subunit - pu
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.