LINF_130016200

DNA-directed RNA polymerase I subunit - putative
Leishmania infantum JPCM5 OG6: OG6_101548 OG7: OG7_0007040 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_360050600 ⚠
DNA-directed RNA polymerase I subunit - putat
— OG7
LINF_310024500 ⚠
hypothetical protein - conserved
— Both
LINF_300029800 ⚠
hypothetical protein - conserved
— Both
LINF_280032100 ⚠
hypothetical protein - conserved
— Both
LINF_350039000 ⚠
Putative death-receptor fusion protein (DUF24
— Both
LINF_360032000 ⚠
hypothetical protein - conserved
— Both
LINF_330034800 ⚠
Unc104-like kinesin - putative
— OG6
LINF_360067400 ⚠
Rab3 GTPase-activating protein regulatory sub
— Both
LINF_260021600 ⚠
hypothetical protein - conserved
— Both
LINF_360066200 ⚠
hypothetical protein - conserved
— Both
LINF_350027000 ⚠
hypothetical protein - conserved
— Both
LINF_290021000 ⚠
hypothetical protein - conserved
— Both
LINF_270022300 ⚠
DNA-directed RNA polymerase II-like protein
— Both
LINF_190009100 ⚠
DNA-directed RNA polymerase III subunit C11 -
— OG7
LINF_170011700 ⚠
ATPase family associated with various cellula
— OG7
LINF_340022600 ⚠
kinesin - putative
— OG6
LINF_300031400 ⚠
replication factor C - subunit 2 - putative
— OG7
LINF_350037900 ⚠
replication factor C - subunit 3 - putative
— OG7
LINF_270011500 ⚠
replication factor C - subunit 4 - putative
— OG7
LINF_240015100 ⚠
replication factor C - subunit 1 - putative
— OG7
LINF_360078900 ⚠
ATPase - putative
— OG7
LINF_340026700 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_340048400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_320013100 ⚠
cyclin 9 - putative
— OG7
LINF_250011500 ⚠
RNA polymerase I second largest subunit - put
— OG7
LINF_190011500 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LINF_180013100 ⚠
DNA-directed RNA polymerase I subunit RPB5z -
— OG7
LINF_340039800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LINF_090018000 ⚠
DNA-directed RNA polymerase III subunit - pu
— OG7
LINF_100008700 ⚠
hypothetical protein - conserved
— Both
LINF_320018500 ⚠
RNA polymerase-like protein - putative
— Both
LINF_200016100 ⚠
MORN repeat-containing protein
— Both
LINF_280027200 ⚠
DNA-directed RNA polymerase-like protein
— Both
LINF_280006100 ⚠
DNA-direcetd RNA polymerase II - subunit 9 -
— Both
LINF_250006500 ⚠
DNA-directed RNA polymerase I subunit - putat
— Both
LINF_180013000 ⚠
DNA-directed RNA polymerase II/III subunit -
— Both
LINF_190011400 ⚠
hypothetical protein - conserved
— Both
LINF_090022800 ⚠
hypothetical protein - conserved
— Both
LINF_080006000 ⚠
hypothetical protein - conserved
— Both
LINF_280013400 ⚠
RNA polymerase B subunit RPB8 - putative
— Both
LINF_150020800 ⚠
ubiquitin hydrolase - putative
— Both
LINF_210019300 ⚠
hypothetical protein - conserved
— Both
LINF_200016000 ⚠
hypothetical protein - conserved
— Both
LINF_200010300 ⚠
DNA-directed RNA polymerase 2 - RPB12 subunit
— Both
LINF_110005500 ⚠
protein kinase - putative
— Both
LINF_080013500 ⚠
Beta-lactamase superfamily domain containing
— Both
LINF_200013100 ⚠
hypothetical protein - conserved
— Both
LINF_010008600 ⚠
hypothetical protein - conserved
— Both
LINF_200005000 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.