LINF_350039000

Putative death-receptor fusion protein (DUF2428) - putative
Leishmania infantum JPCM5 OG6: OG6_146318 OG7: OG7_0006293 113 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 113 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_350037900 ⚠
replication factor C - subunit 3 - putative
— OG7
LINF_230023800
Inositol hexakisphosphate - putative
— Both
LINF_220021200
ATP-dependent DEAD/H RNA helicase - putative
— OG6
LINF_160012700 ⚠
ubiquitin hydrolase - putative
— Both
LINF_320040200 ⚠
chaperonin alpha subunit - putative
— +4 more Both
LINF_150017300
protein phosphatase 2A regulatory subunit - p
— Both
LINF_340034000
hypothetical protein - conserved
— Both
LINF_010009400 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LINF_040008600
hypothetical protein - conserved
— Both
LINF_060013800
hypothetical protein - conserved
— Both
LINF_130016200 ⚠
DNA-directed RNA polymerase I subunit - putat
— Both
LINF_250019300 ⚠
RNA polymerase subunit RPB10 - putative
— Both
LINF_180020000
Protein of unknown function (DUF3648) - putat
— Both
LINF_360071400
hypothetical protein - conserved
— Both
LINF_360032200
hypothetical protein - conserved
— Both
LINF_360015500
hypothetical protein - conserved
— Both
LINF_360032000
hypothetical protein - conserved
— Both
LINF_360067400
Rab3 GTPase-activating protein regulatory sub
— Both
LINF_340050900
coatomer alpha subunit - putative
— Both
LINF_360066200 ⚠
hypothetical protein - conserved
— Both
LINF_290034500
serine/threonine-protein kinase Nek - putativ
— OG6
LINF_060007000
hypothetical protein - conserved
— Both
LINF_300040000 ⚠
protein mkt1 - putative
— Both
LINF_300017600 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_210009400 ⚠
Peptidase C19 - ubiquitin carboxyl-terminal h
— OG7
LINF_240011200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_170008600 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_170011700 ⚠
ATPase family associated with various cellula
— OG7
LINF_300031400 ⚠
replication factor C - subunit 2 - putative
— OG7
LINF_350054100 ⚠
proteasome alpha 1 subunit - putative
— OG7
LINF_320013100 ⚠
cyclin 9 - putative
— OG7
LINF_210014100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LINF_310020100 ⚠
Cold-shock' DNA-binding domain containing pro
— OG7
LINF_360005800 ⚠
leucine carboxyl methyltransferase - putative
— OG7
LINF_340039800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LINF_090019000 ⚠
hypothetical protein - conserved
— OG7
LINF_340048400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_210026800 ⚠
proteasome alpha 2 subunit - putative
— OG7
LINF_140008100 ⚠
proteasome alpha 3 subunit - putative
— OG7
LINF_130022100 ⚠
chaperonin TCP20 - putative
— +3 more OG7
LINF_110007300 ⚠
proteasome alpha 7 subunit - putative
— OG7
LINF_360022300 ⚠
proteasome subunit alpha type-1 - putative
— OG7
LINF_360078900 ⚠
ATPase - putative
— OG7
LINF_290017100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_110006300 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LINF_350055500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_350014200 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LINF_240015100 ⚠
replication factor C - subunit 1 - putative
— OG7
LINF_270011500 ⚠
replication factor C - subunit 4 - putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.