LINF_210014100

Temperature dependent protein affecting M2 dsRNA replication - putative
Leishmania infantum JPCM5 OG6: OG6_143822 OG7: OG7_0013037 100 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 100 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_100018400 ⚠
PAB1-binding protein - putative
— OG7
LINF_150018300 ⚠
glutamate dehydrogenase
— OG7
LINF_270006200 ⚠
hypothetical protein - conserved
— OG7
LINF_350015100 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LINF_150006500 ⚠
zinc finger (CCCH type) protein - putative
— OG7
LINF_150017300 ⚠
protein phosphatase 2A regulatory subunit - p
— OG7
LINF_180020000 ⚠
Protein of unknown function (DUF3648) - putat
— OG7
LINF_010009400 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG7
LINF_340039800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LINF_110013800 ⚠
hypothetical protein - conserved
— OG7
LINF_090015700 ⚠
translation-associated element 2 - putative
— OG7
LINF_210016600 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LINF_100017900 ⚠
Eukaryotic translation initiation factor 4 ga
— OG7
LINF_350014900 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LINF_260009900 ⚠
DNA polymerase sigma-like protein
— OG7
LINF_360049000 ⚠
hypothetical protein
— OG7
LINF_040010000 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LINF_320005100 ⚠
nuclear segregation protein - putative
— OG7
LINF_080013500 ⚠
Beta-lactamase superfamily domain containing
— OG7
LINF_180018700 ⚠
hypothetical protein
— OG7
LINF_180018900 ⚠
hypothetical protein - conserved
— OG7
LINF_090019000 ⚠
hypothetical protein - conserved
— OG7
LINF_090019100 ⚠
hypothetical protein - conserved
— OG7
LINF_150012900 ⚠
hypothetical protein - conserved
— OG7
LINF_280007200 ⚠
hypothetical protein - conserved
— OG7
LINF_340048400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_360067400 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG7
LINF_060007000 ⚠
hypothetical protein - conserved
— OG7
LINF_070011000 ⚠
hypothetical protein - conserved
— OG7
LINF_170008600 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_330038900 ⚠
hypothetical protein - conserved
— OG7
LINF_360015500 ⚠
hypothetical protein - conserved
— OG7
LINF_280006100 ⚠
DNA-direcetd RNA polymerase II - subunit 9 -
— OG7
LINF_360071400 ⚠
hypothetical protein - conserved
— OG7
LINF_360032200 ⚠
hypothetical protein - conserved
— OG7
LINF_300006600 ⚠
leucine-rich repeat protein - putative
— OG7
LINF_190009100 ⚠
DNA-directed RNA polymerase III subunit C11 -
— OG7
LINF_360066200 ⚠
hypothetical protein - conserved
— OG7
LINF_340008100 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_320013100 ⚠
cyclin 9 - putative
— OG7
LINF_050006400 ⚠
Leucine Rich repeat/Leucine rich repeat/Leuci
— OG7
LINF_260010000 ⚠
Leucine rich repeat/Leucine Rich Repeat/Leuci
— OG7
LINF_350039000 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LINF_280034600 ⚠
Uncharacterized ACR - COG1678 - putative
— OG7
LINF_090016100 ⚠
hypothetical protein - conserved
— OG7
LINF_040010700 ⚠
DENN (AEX-3) domain containing protein - puta
— OG7
LINF_080006000 ⚠
hypothetical protein - conserved
— OG7
LINF_280019900 ⚠
hypothetical protein - conserved
— OG7
LINF_150006300 ⚠
zinc finger (CCCH type) protein - putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.