LINF_040010700

DENN (AEX-3) domain containing protein - putative
Leishmania infantum JPCM5 OG6: OG6_157986 OG7: OG7_0052278 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_360066200 ⚠
hypothetical protein - conserved
— Both
LINF_360036500
hypothetical protein - conserved
— Both
LINF_210026400
hypothetical protein - conserved
— Both
LINF_240009700
Leucine rich repeat/Leucine Rich repeats (2 c
— Both
LINF_210007200
Leucine Rich repeat/CHAT domain containing pr
— Both
LINF_080006000
hypothetical protein - conserved
— Both
LINF_150018300
glutamate dehydrogenase
— Both
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— Both
LINF_350015300
hypothetical protein - conserved
— Both
LINF_160017100 ⚠
WW domain containing protein - putative
— Both
LINF_090020400 ⚠
PPPDE putative peptidase domain containing pr
— Both
LINF_210010100
vacuolar sorting-associated-like protein
— Both
LINF_040005200
cAMP-specific phosphodiesterase - putative
— Both
LINF_010009400 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LINF_040008600
hypothetical protein - conserved
— Both
LINF_340039800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LINF_110006300 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LINF_100007000 ⚠
MORN repeat - putative
— OG7
LINF_210009400 ⚠
Peptidase C19 - ubiquitin carboxyl-terminal h
— OG7
LINF_260017600 ⚠
hypothetical protein - conserved
— OG7
LINF_290017100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_140018100 ⚠
ras-like small GTPases - putative
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_350014200 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_320013100 ⚠
cyclin 9 - putative
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_090020500 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LINF_170008600 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_260030700 ⚠
hypothetical protein
— OG7
LINF_320021300 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_360082400 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_350028700 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_260019200 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LINF_180011100 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_350055500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_200007900 ⚠
developmentally regulated phosphoprotein-like
— OG7
LINF_210014100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LINF_090019000 ⚠
hypothetical protein - conserved
— OG7
LINF_340048400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_260030600 ⚠
hypothetical protein
— OG7
LINF_360055000 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_240011200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_340046700 ⚠
Histidine kinase- - DNA gyrase B- - and HSP90
— OG7
LINF_100006100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_320019000 ⚠
PPPDE putative peptidase domain containing pr
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.