LINF_220021200

ATP-dependent DEAD/H RNA helicase - putative
Leishmania infantum JPCM5 OG6: OG6_126543 OG7: OG7_0000698 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_360015500
hypothetical protein - conserved
— OG6
LINF_330008000
WD domain - G-beta repeat - putative
— OG6
LINF_290034500
serine/threonine-protein kinase Nek - putativ
— OG6
LINF_330034800
Unc104-like kinesin - putative
— OG6
LINF_330023100
hypothetical protein - conserved
— OG6
LINF_280007200
hypothetical protein - conserved
— OG6
LINF_260016200
Axonemal dynein light chain - putative
— OG6
LINF_300010000
hypothetical protein - conserved
— OG6
LINF_350039000
Putative death-receptor fusion protein (DUF24
— OG6
LINF_320020400
Microtubule-binding protein MIP-T3 - putative
— OG6
LINF_300040000
protein mkt1 - putative
— OG6
LINF_330038900
hypothetical protein - conserved
— OG6
LINF_360067400
Rab3 GTPase-activating protein regulatory sub
— OG6
LINF_290015500
kinesin - putative
— OG6
LINF_300029800
hypothetical protein - conserved
— OG6
LINF_280034600
Uncharacterized ACR - COG1678 - putative
— OG6
LINF_340022300
hypothetical protein - conserved
— OG6
LINF_350022200
casein kinase II - putative
— OG6
LINF_300005500
MATH domain containing protein - putative
— OG6
LINF_360071400
hypothetical protein - conserved
— OG6
LINF_360032200
hypothetical protein - conserved
— OG6
LINF_360073800 ⚠
target of rapamycin (TOR) kinase 1 - putative
— OG6
LINF_230017400
hypothetical protein - conserved
— OG6
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG6
LINF_060007000
hypothetical protein - conserved
— OG6
LINF_180020000
Protein of unknown function (DUF3648) - putat
— OG6
LINF_220011100
proteasome regulatory ATPase subunit 1 - puta
— OG6
LINF_090019500
AAA family ATPase - putative
— OG6
LINF_040008600
hypothetical protein - conserved
— OG6
LINF_010009400
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
LINF_120005000
translation initiation factor EIF-2b alpha su
— OG6
LINF_150017300
protein phosphatase 2A regulatory subunit - p
— OG6
LINF_160012700
ubiquitin hydrolase - putative
— OG6
LINF_240025800
hypothetical protein - conserved
— OG6
LINF_260024800
microtubule-associated protein - putative
— OG6
LINF_350038200 ⚠
60S ribosomal subunit protein L31 - putative
— OG6
LINF_250025200
Not1 N-terminal domain - CCR4-Not complex com
— OG6
LINF_320012100
OSM3-like kinesin - putative
— OG6
LINF_350038300 ⚠
60S ribosomal subunit protein L31 - putative
— OG6
LINF_250020500
Putative intraflagellar transport protein A1
— OG6
LINF_290018200
COPII coat assembly protein sec16 - putative
— OG6
LINF_360066200
hypothetical protein - conserved
— OG6
LINF_320008200
intraflagellar transport protein 140 - putati
— OG6
LINF_290017700
hypothetical protein - conserved
— OG6
LINF_340008100
WD domain - G-beta repeat - putative
— OG6
LINF_270028900
WD domain - G-beta repeat - putative
— OG6
LINF_070006200
Sec7 domain containing protein - putative
— OG6
LINF_060007900 ⚠
5'-3' exoribonuclease A - putative
— OG6
LINF_190014600
CAP-Gly domain containing protein - putative
— OG6
LINF_100017700
hypothetical protein - conserved
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.