LINF_160019300

DNA-directed rna polymerase I largest subunit - putative
Leishmania infantum JPCM5 OG6: OG6_101773 OG7: OG7_0001854 179 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 179 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_080010200 ⚠
ribose-phosphate pyrophosphokinase - putative
— Both
LINF_200005000 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— +1 more OG7
LINF_310006600 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— +1 more OG7
LINF_080016200 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LINF_330028000 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_360063600 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_250011500 ⚠
RNA polymerase I second largest subunit - put
— +3 more Both
LINF_290006300 ⚠
RNA polymerase subunit - putative
— OG7
LINF_190011500 ⚠
DNA-directed RNA polymerases I and III subuni
— +1 more Both
LINF_310038500 ⚠
acetyl-CoA carboxylase - putative
— Both
LINF_240014300 ⚠
DNA replication licensing factor MCM5 - putat
— OG7
LINF_160008900 ⚠
tubulin tyrosine ligase - putative
— Both
LINF_190009100 ⚠
DNA-directed RNA polymerase III subunit C11 -
— OG7
LINF_280006100 ⚠
DNA-direcetd RNA polymerase II - subunit 9 -
— OG7
LINF_290024000 ⚠
histone H2A - putative
— OG7
LINF_210016800 ⚠
histone H2A - putative
— OG7
LINF_290024100 ⚠
histone H2A - putative
— OG7
LINF_210016700 ⚠
histone H2A - putative
— OG7
LINF_290023900 ⚠
histone H2A - putative
— OG7
LINF_210016900 ⚠
histone H2A - putative
— OG7
LINF_290007600 ⚠
Tubulin-tyrosine ligase family - putative
— OG7
LINF_320036500 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_300028200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_350054800 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_180008700 ⚠
tubulin tyrosine ligase protein - putative
— OG7
LINF_110008900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LINF_270033100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_200012800 ⚠
tubulin-tyrosine ligase - putative
— OG7
LINF_090008100 ⚠
DNA replication licensing factor MCM4 - puta
— OG7
LINF_330036300 ⚠
DNA replication licensing factor MCM3 - putat
— OG7
LINF_160005200 ⚠
Holliday junction DNA helicase ruvB N-terminu
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_360043900 ⚠
polyubiquitin - putative
— OG7
LINF_240029100 ⚠
cullin-like protein-like protein
— OG7
LINF_260017600 ⚠
hypothetical protein - conserved
— OG7
LINF_230026400 ⚠
neutral sphingomyelinase activation associate
— OG7
LINF_360011600 ⚠
ubiquitin/ribosomal protein S27a - putative
— OG7
LINF_310028300 ⚠
ubiquitin-fusion protein
— OG7
LINF_140018100 ⚠
ras-like small GTPases - putative
— OG7
LINF_330037100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LINF_320019300 ⚠
RNA guanylyltransferase - putative
— OG7
LINF_290025700 ⚠
dihydrolipoamide dehydrogenase - putative
— OG7
LINF_360019700 ⚠
adenylate kinase - putative
— OG7
LINF_280030800 ⚠
DNA replication licensing factor MCM6 - putat
— OG7
LINF_140019100 ⚠
ubiquitin/ribosomal protein S27a - putative
— OG7
LINF_350040400 ⚠
zinc finger protein - putative
— OG7
LINF_360079500 ⚠
adaptin complex 1 subunit - putative
— OG7
LINF_040010000 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LINF_260009900 ⚠
DNA polymerase sigma-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.